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This safety notice is designed to inform you about potential risks when using this medication. Please read the details carefully and consult your healthcare provider if you have any concerns.

• Excessive Fluoride Consumption: Overconsumption of fluoride may lead to a condition known as fluorosis, which can alter the appearance of your child's teeth. Additionally, ingesting large amounts of fluoride at once may result in symptoms such as burning sensations in the mouth, sore tongue, nausea, vomiting, diarrhea, stomach pain, increased salivation, and vomiting blood. Should your child exhibit any of these symptoms while using Floriva (a combination of vitamin D and fluoride), it is crucial to contact their healthcare provider or reach out to a Poison Control Center immediately at 1-800-222-1222.

There are no specific contraindications noted for this medication.

When taking Floriva, it's important to be aware of potential interactions with other substances that can affect its effectiveness. Here are some key considerations:

Calcium-Containing Products: Calcium can interfere with the absorption of fluoride, a key component of Floriva. To ensure optimal absorption, avoid consuming calcium-rich foods and beverages—such as milk, yogurt, and other dairy products—as well as calcium supplements and antacids containing calcium, within two hours before or after taking Floriva.

Aluminum and Magnesium-Containing Antacids or Laxatives: Similar to calcium, products containing aluminum or magnesium can reduce the effectiveness of fluoride. It's advisable to avoid taking antacids or laxatives that contain these minerals within two hours of your Floriva dose.

Other Multivitamin Products: Taking multiple multivitamin supplements simultaneously can lead to an excessive intake of certain vitamins and minerals, increasing the risk of side effects. To prevent this, avoid using other multivitamin products within two hours before or after taking Floriva.

Antibiotics: Some antibiotics may interact with the components of Floriva. To minimize potential interactions, avoid taking antibiotics within two hours before or after your Floriva dose.

Additional Fluoride Sources: Excessive fluoride intake can lead to dental fluorosis, a condition that affects tooth enamel. Be mindful of other fluoride sources, such as fluoridated water and toothpaste. Consult your healthcare provider to determine if additional fluoride supplementation is necessary.

Other Medications: Floriva may interact with certain medications, including anticoagulants like warfarin, bile acid sequestrants such as cholestyramine, and medications like orlistat. These interactions can affect the absorption and effectiveness of Floriva or the other medications. Always inform your healthcare provider about all medications and supplements you are currently taking to assess potential interactions.

By being aware of these interactions and timing your doses appropriately, you can help ensure that Floriva works effectively to support your dental health.