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Fluopar is a topical medication containing fluocinonide, a potent corticosteroid, and dimethicone, a skin protectant. While effective in treating certain skin conditions, it's important to be aware of potential risks associated with its use.

One significant risk is the suppression of the hypothalamic-pituitary-adrenal (HPA) axis. This system regulates various body functions, including stress response and immune activity. Prolonged or extensive use of Fluopar can lead to reversible suppression of this axis, potentially resulting in conditions like Cushing's syndrome, characterized by weight gain and high blood pressure, or hyperglycemia, an increase in blood sugar levels. To minimize this risk, it's recommended not to use Fluopar for more than two consecutive weeks or exceed a total dosage of 60 grams per week.

Additionally, applying Fluopar to large areas of the body, using it under occlusive dressings, or applying it to areas with compromised skin integrity can increase systemic absorption, heightening the risk of these systemic effects. Therefore, it's advisable to avoid using Fluopar on the face, groin, or underarms, and to refrain from covering treated areas unless directed by a healthcare provider.

In pediatric patients, the risk of systemic toxicity is higher due to their larger skin surface area relative to body mass. Consequently, the safety and efficacy of Fluopar in children under 12 years of age have not been established, and its use in this age group is not recommended.

If a skin infection is present or develops during treatment, appropriate antifungal or antibacterial therapy should be initiated. If the infection does not respond promptly, discontinuation of Fluopar may be necessary until the infection is adequately controlled.

It's crucial to use Fluopar exactly as prescribed and to consult a healthcare provider if there are any concerns or if the condition does not improve within the recommended treatment period.