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Dexmethylphenidate requires careful management due to its potential risks. Here are key safety considerations:

• Risk of Heart and Blood Pressure Issues: Misusing or abusing dexmethylphenidate can lead to severe, possibly fatal, cardiovascular complications.
• Potential for Habit Formation: This medication can be addictive. Use it with caution if you have a history of mental health or substance use disorders. Inform your healthcare provider if you or your family has a history of substance abuse.
• Adherence to Prescribed Use: Avoid altering the dosage, frequency, or method of use without medical guidance. Doing so may reduce the medication's effectiveness, lead to dependence, or cause unusual thoughts and behaviors.
• Monitoring Post-Use: If you have been using dexmethylphenidate for an extended period or at high doses, your doctor might monitor you after discontinuation to manage any withdrawal symptoms or other effects.

Always follow your healthcare provider's instructions and communicate any concerns regarding your treatment.

This medication may cause some common side effects, including trouble sleeping, nervousness, dizziness, dry mouth, heartburn, nausea, stomach pain, headache, loss of appetite, or weight loss. These effects are usually mild and tend to diminish as your body adjusts to the treatment. However, if they persist or worsen, it's important to inform your healthcare provider.

Be aware that this medication might increase your blood pressure. Regular monitoring is recommended, and you should report any high readings to your healthcare professional. In rare cases, serious side effects can occur. These include signs of blood flow issues in fingers or toes such as coldness, numbness, pain, or skin color changes, unusual wounds, rapid or irregular heartbeat, and significant mental or mood changes like agitation, aggression, or thoughts of suicide.

Seek immediate medical attention if you experience very serious side effects such as fainting, seizures, symptoms of a heart attack (chest, jaw, or left arm pain, shortness of breath, unusual sweating), or signs of a stroke (weakness on one side of the body, trouble speaking, sudden vision changes, confusion). Additionally, although rare, males may encounter a painful or prolonged erection lasting four or more hours; if this happens, discontinue use and seek urgent medical help to prevent lasting damage.

Serious allergic reactions to this medication are uncommon but require immediate medical intervention if you notice symptoms such as rash, itching/swelling, severe dizziness, or trouble breathing. This overview does not cover all possible side effects. Always consult your healthcare provider if you notice any other unusual symptoms.

Avoid using MAO inhibitors with this medication, as it can lead to a severe, possibly life-threatening interaction. Do not take MAO inhibitors such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while you are on this medication. Additionally, most MAO inhibitors should not be used for two weeks before starting this treatment. Consult your doctor for guidance on when to begin or discontinue the medication.

Dexmethylphenidate is closely related to Methylphenidate, so avoid using any medications containing methylphenidate while taking dexmethylphenidate.

This medication could interfere with certain medical or laboratory tests, such as brain scans for Parkinson's disease, potentially leading to inaccurate results. Ensure that all healthcare professionals and lab staff are informed that you are taking this medication.