Galafold
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$33,148.62
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AlbertsonsPowered byAbout Galafold
Drug Details
Migalastat, marketed as Galafold, is an oral medication prescribed for the long-term management of Fabry disease, a rare inherited disorder. In individuals with Fabry disease, the enzyme alpha-galactosidase A is deficient or malfunctioning, leading to the accumulation of a fatty substance in the kidneys, heart, and other organs. This drug functions as a pharmacologic chaperone, binding to the faulty enzyme to improve its functionality. By doing so, it helps the enzyme reach its target location in the body to effectively break down the excess fatty deposits. This can alleviate symptoms such as abdominal cramps, diarrhea, burning pain in the hands and feet, heat intolerance, skin rash, and reduce the risks of kidney and heart disease or stroke. Galafold is available only through specialty pharmacies, and potential users should consult a genetic counselor to determine their suitability for the treatment. Always discuss with a healthcare professional before starting or changing any medication regimen.
Price history for Galafold
14 Capsules, 123MG
Average retail price for Galafold
Average SaveHealth price for Galafold
Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.
*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.
Galafold dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 123MG | 14 Capsules | $33,148.62 | $2,367.76 |
Galafold FAQs
Galafold is used for the treatment of Fabry disease in adults who have a specific genetic mutation that is amenable to this therapy. Fabry disease is a rare genetic disorder that affects the body's ability to break down a certain type of fat, leading to a buildup that can cause various symptoms and complications. Galafold works by stabilizing the enzyme that is deficient in individuals with Fabry disease, helping to reduce the accumulation of the fat substrate.
Galafold is not an enzyme replacement therapy. It is a pharmacological chaperone used to treat Fabry disease in patients with certain genetic mutations. It works by stabilizing the body's own dysfunctional enzyme, rather than replacing it.
The cost of Galafold can vary depending on factors such as the pharmacy, location, insurance coverage, and any available discounts or assistance programs. It is recommended to contact a local pharmacy or healthcare provider for the most accurate and up-to-date pricing information. Additionally, patients may explore patient assistance programs offered by the manufacturer for potential financial support.
The cost of Fabry disease treatment can vary significantly depending on the specific therapy, the healthcare provider, and the region. Enzyme replacement therapies, such as Fabrazyme or Replagal, are commonly used and can be quite expensive, often reaching several hundred thousand dollars per year. Insurance coverage, financial assistance programs, and regional healthcare policies can also influence the out-of-pocket cost for patients. It is advisable for individuals to consult with their healthcare provider or insurance company for precise cost information tailored to their situation.
Galafold (migalastat) works by stabilizing certain mutant forms of the enzyme alpha-galactosidase A in patients with Fabry disease. It acts as a pharmacological chaperone, binding to the active site of the enzyme, which helps it fold correctly and enhances its stability and activity. This allows the enzyme to be trafficked to the lysosome, where it can break down the substrate globotriaosylceramide (GL-3), reducing its accumulation in the body.