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The use of Jolessa (levonorgestrel / ethinyl estradiol), a combined oral contraceptive, requires careful consideration due to potential health risks and contraindications. Below are the critical safety warnings and instructions for this medication:

• Smoking and Heart Risks: Females who smoke, especially those over 35 years old, should avoid using this medication. Smoking increases the likelihood of severe cardiovascular issues, such as stroke, heart attack, and blood clots. Discuss alternative birth control methods with your healthcare provider.

• Blood Clot Risks: Jolessa may elevate the risk of developing blood clots in various parts of the body, including the lungs, legs, brain, and heart. This risk is heightened for women over 35, those with recent surgery, or individuals who are obese, have high blood pressure, or diabetes. Seek immediate medical attention if you experience symptoms indicative of a blood clot.

• Cancer Risks: There is a potential increased risk of breast and cervical cancer associated with long-term use of Jolessa. Avoid this medication if you have a history of breast cancer or are experiencing unexplained vaginal bleeding. Regular check-ups and self-exams are recommended for early detection.

• Liver Concerns: Jolessa can occasionally cause liver problems, including liver damage or tumors. Avoid this contraceptive if you have existing liver issues, and consult your healthcare provider if you notice symptoms like fatigue, abdominal pain, or jaundice.

• Metabolic Effects: This medication may raise blood sugar levels and triglycerides, particularly in individuals with diabetes or a history of high triglycerides. Regular monitoring of blood sugar is advised.

• Blood Pressure: Jolessa can lead to increased blood pressure. Regular monitoring is necessary, and those with uncontrolled high blood pressure should consider alternative options.

• Headaches: While headaches are a typical side effect, any new or severe headaches should be reported to your healthcare provider.

• Irregular Bleeding: Breakthrough bleeding may occur during the first few months of use. Consult your healthcare provider if irregular bleeding persists.

• Depression: Report any new or worsening symptoms of depression to your healthcare provider, as this may necessitate discontinuation of the medication.

• Gallbladder Disease: There may be an increased risk of gallstones; discuss your medical history with your healthcare provider before starting Jolessa.

• Swelling Attacks: Individuals with hereditary angioedema may experience swelling attacks; seek immediate medical assistance if symptoms occur.

• Drug Interactions: Certain medications can affect the effectiveness of Jolessa, such as those for epilepsy or hepatitis C. Inform your healthcare provider about all medications you are taking to avoid interactions.

• Contraindications: Do not use Jolessa if you have a history of blood clots, stroke, heart attack, liver disease, or certain types of cancer. Pregnant individuals and those using specific hepatitis C treatments should also avoid this contraceptive.

Always discuss your medical history and concerns with your healthcare provider to determine the safest and most effective birth control method for you.

When taking this medication, some individuals may experience common side effects such as headache, nausea, acne, breast tenderness, weight changes, and swelling of the ankles or feet due to fluid retention. Occasionally, users might notice changes in their menstrual cycle, including spotting or heavier periods, particularly in the initial months of use. It's important to be aware that you should only have your period during the inactive pill week every three months. If your period does not occur during this time, consult your healthcare provider for a possible pregnancy test.

While these effects are generally mild, if they become bothersome or persist, it is advisable to consult a healthcare professional. Mood swings, mild depression, and period cramps are also reported by some users and should be discussed with a healthcare provider if they cause significant discomfort.

There are rare but serious side effects that necessitate immediate medical attention. These include symptoms indicative of a heart attack or stroke, such as chest pain, sudden dizziness, severe headaches, difficulty speaking, and sudden vision changes. Other critical conditions to be aware of include blood clots in the legs or lungs, with symptoms like leg swelling, chest pain, trouble breathing, or a racing heart. Additionally, serious allergic reactions, although rare, may occur, presenting as rash, itching, severe dizziness, or difficulty breathing.

This medication may also elevate blood pressure, so regular monitoring is advisable. If you notice any unusual or severe side effects not listed here, seek medical advice promptly. Always prioritize clear communication with your healthcare provider regarding any adverse effects experienced during the use of this medication.