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When considering the use of Isibloom, a combined oral contraceptive (COC), it is crucial to be aware of specific safety warnings and contraindications to ensure your well-being. Please review the following information thoroughly and discuss any concerns with your healthcare provider.

• Smoking and Heart Risks: Smoking while using Isibloom significantly raises the risk of serious cardiovascular events such as strokes, heart attacks, and blood clots. This risk is particularly high for individuals over 35 years old. The more you smoke, the greater the risk. If you smoke, consider consulting your healthcare provider about alternative birth control methods.

• Blood Clots: Although the overall risk is low, Isibloom can increase the likelihood of developing blood clots, which can lead to conditions like deep vein thrombosis (DVT), pulmonary embolism (PE), strokes, or heart attacks. This risk is elevated for those over 35 who smoke, individuals over 40, those recently having surgery with extended bed rest, those starting Isibloom within a month after childbirth, individuals classified as obese, and those with high blood pressure, high cholesterol, or diabetes.

• Cancer Risks: There is a potential association between prolonged use of Isibloom and increased risk of breast and cervical cancer. If you have a history of breast cancer or have been using COCs for an extended period, discuss your risks with your healthcare provider.

• Liver Issues: Isibloom is not recommended for individuals with liver problems. Although rare, COCs can increase the risk of liver damage or benign tumors. This risk was higher with older versions of COCs with higher estrogen doses.

• Blood Sugar and Cholesterol Levels: Isibloom may elevate blood sugar levels, posing a higher risk for those with prediabetes or diabetes. It can also affect cholesterol and triglyceride levels, particularly for those with a personal or family history of high triglycerides.

• High Blood Pressure: The use of Isibloom may increase blood pressure, especially with prolonged use or in older individuals. Consult your healthcare provider if you have kidney issues or pre-existing high blood pressure.

• Headaches and Migraines: Headaches are a common side effect. However, if you experience new or worsening migraines, frequent headaches, or severe headaches, seek medical advice promptly.

• Irregular Bleeding: Spotting or breakthrough bleeding may occur, especially during the first three months. Inform your healthcare provider if bleeding persists or if your periods stop.

• Depression: Report any signs of depression or worsening symptoms to your healthcare provider. In severe cases, discontinuation of Isibloom might be necessary.

• Drug Interactions: Inform your healthcare provider of all medications you are taking, as some can affect the efficacy of Isibloom or increase side effects. Examples include carbamazepine and phenytoin. Use an additional birth control method while using these medications.

Contraindications: Do not use Isibloom if you:

• Smoke and are over 35 years old.
• Have medical conditions or a history of blood clots, coronary artery disease, stroke, certain heart issues, or uncontrolled high blood pressure.
• Have diabetes with complications or certain types of headaches.
• Are undergoing major surgery with prolonged bed rest.
• Have undiagnosed abnormal vaginal bleeding, breast or endometrial cancer, liver issues, or are currently pregnant.
• Are taking specific hepatitis C medications.

Always consult your healthcare provider before starting Isibloom to ensure it is safe for your individual circumstances.

When taking this medication, you may experience some common side effects, which are generally mild and often improve over time. These can include nausea, vomiting, stomach cramps, bloating, spotting or breakthrough bleeding, changes in menstrual flow, breast tenderness, headaches, and weight fluctuations. If these symptoms persist or become bothersome, it's advisable to consult your healthcare provider.

Other side effects that may occur include spotty darkening of the skin, difficulty wearing contact lenses, changes in sex drive, acne, changes in appetite, increased blood pressure, depression, and yeast infections. While these effects are less common, it’s important to monitor them and discuss any concerns with your healthcare provider.

Serious side effects, although rare, demand immediate medical attention. These include symptoms of a heart attack, such as chest pain, sweating, nausea, or dizziness, or symptoms of a stroke, like sudden numbness or weakness, severe headache, or confusion. Additionally, be aware of signs of deep vein thrombosis, such as leg cramps and swelling, pulmonary embolism indicated by chest pain and trouble breathing, and serious liver problems marked by yellowing skin or eyes. An allergic reaction is very rare but requires urgent care if you notice rash, swelling, severe dizziness, or trouble breathing.

Always be vigilant about any new or worsening symptoms and seek medical advice as needed.