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Methylphenidate requires careful usage due to the potential for severe heart and blood pressure issues if misused or abused. This medication can be addictive and should be administered with caution, particularly in individuals with mental health conditions or a history of substance abuse, including drug or alcohol addiction.

• Before beginning treatment, inform your healthcare provider about any personal or family history of substance use disorders.
• Do not exceed the prescribed dosage, frequency, or duration of use, as misuse can lead to reduced effectiveness, dependency, or unusual thoughts and behaviors.
• Your healthcare provider may continue to monitor you after discontinuation, especially if the medication was taken in high doses or over an extended period.

When taking this medication, you might experience mild side effects such as nervousness, trouble sleeping, loss of appetite, weight loss, dizziness, nausea, vomiting, or headache. These usually subside on their own, but if they persist or worsen, it’s important to consult a healthcare professional. Monitoring your blood pressure is advisable since this medication might cause an increase.

In some cases, more serious side effects can occur. Be alert for signs of blood circulation issues in your fingers or toes, such as coldness, numbness, pain, or color changes. Other serious symptoms to watch for include fast or irregular heartbeat, mood or mental changes like agitation or thoughts of suicide, uncontrolled muscle movements, sudden outbursts, and vision alterations. If you experience any of these, seek medical attention immediately.

Very serious side effects, although rare, require urgent medical help. These include fainting, seizures, heart attack symptoms like chest pain or shortness of breath, and stroke symptoms such as weakness on one side of the body or trouble speaking. Males may rarely experience a painful or prolonged erection lasting over four hours, which needs immediate medical intervention to prevent long-term problems.

Allergic reactions to this medication are uncommon, but should you notice symptoms like rash, itching, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing, seek emergency medical help. If you observe any side effects not mentioned here, it’s important to contact your healthcare provider for further advice.

Using MAO inhibitors alongside this medication can lead to a severe and potentially life-threatening interaction. Do not take MAO inhibitors such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while you are on this treatment. Additionally, most MAO inhibitors should be avoided for two weeks before starting this medication. Consult your doctor about when to begin or discontinue this medication.

Avoid consuming alcohol with this medication, as it could cause the drug to be released too quickly, raising the likelihood of side effects. Methylphenidate is closely related to Dexmethylphenidate; therefore, do not use any dexmethylphenidate-containing products while taking methylphenidate.

This medication might affect certain medical or lab tests, including brain scans for Parkinson's disease, which could result in inaccurate test outcomes. Ensure that all your healthcare providers and lab technicians are aware that you are taking this medication.