Ambrisentan

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ambrisentan

Ambrisentan, also known as Letairis, is a medication prescribed for the treatment of pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the lungs. The drug functions as an endothelin receptor antagonist, which means it blocks the action of endothelin-1, a protein that can constrict blood vessels. By inhibiting this protein, Ambrisentan helps to relax and widen the blood vessels leading from the heart to the lungs, facilitating better blood flow and reducing the workload on the heart. This action helps lower lung blood pressure, slow the progression of symptoms, and enhance the ability to exercise and breathe more easily. Typically taken as one tablet daily, Ambrisentan is generally well-tolerated, though some individuals may experience swelling in the arms or legs. It is important to note that this medication carries a risk of causing serious harm to unborn babies. Therefore, it is available through the Ambrisentan REMS program for those who can become pregnant. Always consult your healthcare provider before starting this medication to ensure it is appropriate for your condition.
Our Letairis coupons are free to use. You can print the coupon, email it to yourself, or receive the Letairis coupon via text message. To get your free discount, show the pharmacist your Letairis savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Letairis prices will update based on your prescription needs. Above our Letairis coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Letairis savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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10MG, Ambrisentan (30 Tablets)

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Walgreens

$2654.60

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$7153.39

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Letairis savings card

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Walgreens

$2654.60

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Letairis dosage forms

The average cost for 30 Tablets of Letairis (ambrisentan) at 5MG is $2654.6 with a free coupon. This is 25.98% off the average retail price of $10217.7
DosageQuantityPrice fromPer unit
5MG30 Tablets$2654.6$88.49
10MG30 Tablets$2654.6$88.49

Letairis Warnings

This medication comes with important safety warnings that need to be carefully considered. Please review the following information and consult with your healthcare provider if you have any questions or concerns:

  • Pregnancy Warning: This medication must not be used during pregnancy due to the risk of serious harm to an unborn child. Female patients must use reliable birth control before, during, and for one month after treatment. Discuss with your doctor the appropriate forms of birth control to use. A pregnancy test is required before starting treatment. If you become pregnant or suspect you might be, contact your healthcare provider immediately. Participation in the Ambrisentan REMS program is required to ensure maximum safety for females who can become pregnant.

  • Fluid Retention: This medication can cause fluid retention, which may lead to swelling or shortness of breath. The risk is heightened if you have a history of heart failure, as it can exacerbate your condition. Notify your healthcare provider if you have any heart issues before beginning treatment. Seek medical advice if you experience symptoms such as shortness of breath, swelling in the legs, ankles, or feet, irregular heartbeat, fatigue, or an inability to exercise.

  • Anemia Risk: There is a potential for this medication to cause a decrease in hemoglobin levels, leading to anemia. This typically occurs within the first few weeks of treatment but usually stabilizes. If you experience symptoms of anemia, such as fatigue or shortness of breath, inform your healthcare provider.

  • Contraindications: Do not use this medication if you are currently pregnant or have been diagnosed with idiopathic pulmonary fibrosis (IPF), as it may cause serious health complications.

Your safety is a priority, and understanding these risks will help ensure the effectiveness of your treatment. Always consult with your healthcare provider for personalized medical advice.

Letairis Side Effects

When taking this medication, you might experience some mild side effects, such as a stuffy or runny nose, flushing, or swelling in the arms or legs. These effects are generally not serious, but if they persist or worsen, it's advisable to consult your healthcare provider for guidance. Additionally, some individuals might encounter sinus infections or inflammation.

While rare, there are more serious side effects to be aware of. If you experience symptoms such as a fast or irregular heartbeat, extreme tiredness, swelling in the ankles or feet, or sudden weight gain, you should seek medical attention immediately. These could indicate fluid buildup in the body, which is a serious condition.

Liver-related side effects, although uncommon, are significant. Signs include persistent nausea or vomiting, loss of appetite, severe stomach pain, dark urine, or yellowing of the skin or eyes. Immediate medical attention is crucial if these symptoms occur, as they may indicate liver injury.

Allergic reactions to this medication are rare but can be severe. Be alert for symptoms like rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing, and seek urgent medical help if they occur. Always monitor for any other unusual effects and consult your healthcare provider if necessary.

Letairis Interactions

A product that may interact with this drug is: sparsentan.
Letairis FAQs
What is Letairis used for?

Letairis is used to treat pulmonary arterial hypertension (PAH) in adults. It helps improve exercise ability and delay the progression of the disease by relaxing blood vessels in the lungs, which lowers blood pressure and improves blood flow.

Yes, Letairis is considered a specialty drug. It is used to treat pulmonary arterial hypertension and typically requires special handling, administration, or monitoring.

Ambrisentan belongs to the drug class known as endothelin receptor antagonists.

Specialty drugs are typically high-cost medications used to treat complex or rare conditions. They often require special handling, administration, or monitoring. Examples of specialty drugs include biologics, such as monoclonal antibodies and gene therapies, as well as medications for conditions like multiple sclerosis, rheumatoid arthritis, cancer, and rare genetic disorders. Specific examples include Humira (adalimumab), Enbrel (etanercept), and Gleevec (imatinib).

The cost of Letairis can vary depending on factors such as the pharmacy, location, insurance coverage, and dosage. It is recommended to check with local pharmacies or consult with a healthcare provider or insurance company for the most accurate and up-to-date pricing information.