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This medication is used to treat skin itching caused by a certain inherited liver condition (Alagille syndrome-ALGS). In ALGS, a substance that your body normally makes (bilirubin) builds up in the liver and causes jaundice. Maralixibat belongs to a class of drugs known as ileal bile acid transporter inhibitors. It helps to lessen symptoms of jaundice such as itching, yellowing eyes/skin, dark urine, and pale-colored stools.