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When considering the use of Lunesta (eszopiclone), it is important to be aware of certain safety risks and warnings. Please carefully review the following information and discuss any concerns with your healthcare provider.

• Abnormal Sleep Behaviors: Taking Lunesta may lead to unusual sleep-related activities, such as sleepwalking, sleep-driving, or preparing food while not fully awake. These behaviors can be dangerous and potentially fatal. If you discover that you have engaged in such activities, inform your doctor immediately. You should not take Lunesta or similar medications (such as zaleplon, zolpidem) if you have experienced these reactions.

• Impaired Alertness: Lunesta can affect alertness and coordination, especially at higher doses, which may persist into the next day. This can increase the risk of falls and accidents, particularly if combined with other sedatives like alcohol, opioids, muscle relaxants, certain antidepressants, and benzodiazepines. Ensure you have at least 7 to 8 hours of sleep after taking Lunesta.

• Behavior Changes and Abnormal Thinking: Rarely, some individuals may experience unusual thoughts or behaviors, such as increased aggression, anxiety, or depression, or even suicidal thoughts. Report any such changes to your healthcare provider promptly.

• Severe Allergic Reactions: Although uncommon, serious allergic reactions can occur, including facial swelling, nausea, vomiting, and difficulty breathing. Seek immediate medical attention if you experience these symptoms and avoid re-taking Lunesta if you've had previous allergic reactions.

• Insomnia Assessment: If Lunesta does not improve your sleep within 7 to 10 days, consult your provider to explore other causes of insomnia that might require different treatments.

• Withdrawal Symptoms: Suddenly stopping Lunesta can lead to withdrawal effects such as insomnia, anxiety, abnormal dreams, nausea, and upset stomach. Do not adjust your dosage or stop the medication without consulting your provider, who can help taper the dose gradually.

• Special Populations: Exercise caution when using Lunesta if you are over 65, have severe liver issues, or other significant health conditions, as these factors may increase sensitivity to the drug's effects. Discuss your medical history and current medications with your provider to determine if you require close monitoring or dosage adjustments.

• Contraindications: Avoid using Lunesta if you have previously experienced abnormal sleep behaviors after taking the medication.

By understanding these risks and closely following your healthcare provider's guidance, you can use Lunesta more safely and effectively.

When taking this medication, some individuals might experience mild side effects such as a bad taste in the mouth, headaches, sleepiness, dizziness, dry mouth, or indigestion. These effects are generally not severe and often manageable. If they persist or become bothersome, consulting with a healthcare provider can help address any concerns.

In some cases, individuals may experience more serious side effects, including memory loss, changes in mood or behavior such as new or worsening depression, anxiety, or hallucinations. If these symptoms occur, it is important to contact a healthcare provider promptly. Additionally, rare but severe allergic reactions may occur, presenting as swelling of the face, tongue, or throat, rash, severe dizziness, and trouble breathing. Should any of these symptoms arise, immediate medical attention is necessary.

There are also reports of individuals performing activities while asleep, such as walking or driving, without recalling these actions later. If you notice unusual thoughts or behaviors, including aggression or confusion, seek medical advice urgently. Although these severe side effects are rare, being vigilant and informed can help ensure your safety while using this medication.

Eszopiclone, known commercially as Lunesta, can interact with a variety of medications, potentially affecting your treatment plan. It's crucial to inform your doctor and pharmacist about all the medications and supplements you are taking, whether they are prescribed, over-the-counter, vitamins, or herbal supplements.

One important interaction to note is with sodium oxybate and related compounds like calcium, magnesium, and potassium oxybate. Combining these with eszopiclone is not recommended. If such a combination is necessary, your healthcare provider might need to adjust your medications.

Additionally, using eszopiclone with medications that cause drowsiness should generally be avoided or closely monitored. These include opioid pain or cough relievers like codeine and hydrocodone, sleep or anxiety medications like Alprazolam and Zolpidem, muscle relaxants such as Carisoprodol, and antihistamines like Cetirizine and diphenhydramine. Alcohol and marijuana can also increase drowsiness when used with eszopiclone.

Moreover, eszopiclone is very similar to zopiclone, so you should not take medications containing zopiclone while on eszopiclone.

Always check the labels on all your medications to ensure they do not contain ingredients that could cause increased drowsiness, and consult your pharmacist to use these products safely.