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Before starting Metafolbic Plus, it's important to consider certain safety precautions:

• Allergic Reactions: Do not use Metafolbic Plus if you have known allergies to any of its ingredients.

• Kidney Stones: If you have a history of kidney stones, consult your doctor before taking this supplement.

• Levodopa Use: Individuals taking levodopa should discuss with their healthcare provider before using Metafolbic Plus.

• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant or planning to become pregnant. Breastfeeding is not recommended while taking this supplement.

• Children: Metafolbic Plus is not recommended for children under 12 years of age.

Always consult your healthcare provider to ensure Metafolbic Plus is appropriate for your specific health needs.

Metafolbic Plus is a dietary supplement combining L-methylfolate, methylcobalamin (vitamin B12), and acetylcysteine. While generally well-tolerated, some individuals may experience side effects. Common side effects include:

• Upset stomach
• Nausea
• Vomiting
• Diarrhea
• Headache These symptoms are typically mild and often resolve as the body adjusts to the supplement. Serious side effects are rare but require immediate medical attention. These may include signs of an allergic reaction, such as rash, hives, itching, swelling of the face, lips, tongue, or throat, difficulty breathing, or swallowing. Additionally, if you experience chest pain, shortness of breath, coughing up blood, difficulty urinating, numbness or weakness in your limbs, severe headache, vision or speech problems, or swelling anywhere in your body, seek medical help promptly. It's important to inform your healthcare provider of any existing health conditions, especially if you have a history of kidney stones, peptic ulcers, or allergies to any components of Metafolbic Plus. If you are pregnant or breastfeeding, consult your doctor before starting this supplement. Always take Metafolbic Plus as directed by your healthcare provider. If you experience any side effects that persist or worsen, contact your doctor. In case of a suspected overdose, seek immediate medical attention.

When taking Metafolbic Plus, it's important to be aware of potential interactions with other medications. This supplement contains L-Methylfolate, Methylcobalamin (vitamin B12), and N-acetylcysteine, which can interact with certain drugs, affecting their effectiveness or increasing the risk of side effects.

Medications That May Interact with Metafolbic Plus:

• Anticoagulants (Blood Thinners): Drugs like Warfarin, anisindione, and dicumarol may have their effects altered when taken with Metafolbic Plus.

• Cholesterol-Lowering Agents: Medications such as Cholestyramine, Colesevelam, and Colestipol can interact with Metafolbic Plus.

• Chemotherapy Agents: Drugs like Capecitabine and Fluorouracil may have interactions with Metafolbic Plus.

• Other Medications: Bortezomib, maralixibat, odevixibat, Orlistat, pafolacianine, and sevelamer are also known to interact with Metafolbic Plus.

Additional Considerations:

• Levodopa: If you're taking levodopa, consult your doctor before using Metafolbic Plus, as there may be interactions.

• Kidney Stones: Individuals with a history of kidney stones should discuss the use of Metafolbic Plus with their healthcare provider.

• Allergies: Inform your doctor if you have any allergies to the components of Metafolbic Plus or other substances.

• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking Metafolbic Plus.

Recommendations:

Always inform your healthcare provider about all the medications, supplements, and over-the-counter drugs you are currently taking. This will help them assess potential interactions and determine if Metafolbic Plus is appropriate for you. Do not start, stop, or change the dosage of any medication without consulting your doctor.