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This medication contains acetaminophen, which can pose serious health risks if not used correctly. Please carefully read the following safety information and consult your healthcare provider if you have any questions or concerns.

• Liver Risks: Excessive acetaminophen intake can lead to severe and potentially fatal liver damage. Adults should not exceed 4000 mg (4 grams) per day, while those with liver issues and children require lower doses. Always consult your healthcare provider or pharmacist for appropriate dosing.

• Drug Interactions: Avoid taking other medications that contain acetaminophen without professional advice, as it is a common ingredient in many over-the-counter and prescription drugs. Check all medication labels and consult your pharmacist if you're uncertain.

• Alcohol Use: Regular alcohol consumption, especially when combined with acetaminophen, increases the risk of liver damage. It is advised to avoid alcohol while using this medication.

• Overdose Warning: Seek immediate medical assistance if an overdose occurs, even if you feel fine. Symptoms of overdose may include nausea, vomiting, loss of appetite, sweating, abdominal pain, extreme fatigue, yellowing of the eyes or skin, and dark urine.

• Potential for Accidental Overdose: This product also contains chlorpheniramine and phenylephrine, which are found in many other cold and flu medications. Combining these can lead to overdose and severe side effects, such as liver failure, seizures, and hallucinations. Inform your healthcare provider about all medications you are taking to avoid these risks.

• Sensitive Populations: Individuals aged 65 and above may experience intensified side effects. Additionally, Norel AD may exacerbate conditions like liver disease, high blood pressure, glaucoma, thyroid disease, diabetes, urinary, or breathing problems. Discuss your medical history with your healthcare provider to determine if this medication is suitable for you.

• Allergic Reactions: Though rare, serious skin reactions such as rash, blisters, or skin peeling can occur. Discontinue use and seek medical attention if any skin changes are observed.

• Contraindications: Do not use this medication if you are taking other drugs containing acetaminophen or if you have taken a monoamine oxidase inhibitor (MAOI) within the past two weeks. Consult your healthcare provider for more information.

This information is essential for the safe use of this medication and should be reviewed with your healthcare provider.

When taking this medication, some common side effects might include feeling drowsy or dizzy, experiencing dry mouth, or having blurry vision. Occasionally, individuals may notice an upset stomach, nausea, or mild nervousness. These effects are usually mild, but if they persist or worsen, it's a good idea to consult with your healthcare provider.

Some people might experience additional side effects such as headaches, constipation, diarrhea, or trouble urinating. While these are less common, they should still be monitored, and any concerns should be discussed with a healthcare professional.

On a more serious note, although rare, some individuals might experience severe side effects that require immediate medical attention. These include mental or mood changes like confusion or hallucinations, shaking, an irregular heartbeat, or seizures. Allergic reactions, while uncommon, can occur and may present as a rash, severe dizziness, or difficulty breathing. Additionally, some might encounter serious skin reactions or liver-related issues, such as severe stomach pain or yellowing of the skin or eyes. If any of these symptoms arise, seeking urgent medical care is crucial. Always be attentive to your body’s reactions and report any other unusual effects to your healthcare provider.

Certain medications can interact with this drug. For instance, ketoconazole and levoketoconazole may cause interactions. Additionally, using MAO inhibitors like isocarboxazid, linezolid, or selegiline while on this drug could lead to severe and potentially life-threatening reactions. It is crucial to avoid MAO inhibitors during treatment and, in most cases, for two weeks before starting this medication. Consult your doctor about the appropriate timing for beginning or discontinuing this medication.

Inform your healthcare provider if you are using other products that may induce drowsiness, including opioid pain relievers (e.g., codeine, hydrocodone), alcohol, cannabis, sleep or anxiety medications (such as alprazolam, lorazepam, zolpidem), muscle relaxants (like carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

Be aware that this medication’s ingredients can be found in various prescription and over-the-counter products, like those for pain, fever, diet, or cough and cold/allergy relief. Using these concurrently may enhance side effects, including rapid heartbeat, high blood pressure, or increased drowsiness. It is advisable to discuss safe use of such products with your pharmacist.

Avoid using any other topical antihistamines, such as diphenhydramine creams, ointments, or sprays, as this may increase side effects. Lastly, this medication might affect the results of certain lab tests, including urine drug screenings and allergy skin tests. Ensure that all lab personnel and your healthcare providers are informed that you are taking this medication.