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When taking this medication, some individuals might experience mild side effects such as constipation or upset stomach. These are generally manageable, but if they persist or worsen, it is advisable to seek guidance from a healthcare professional. Most users of this medication do not encounter serious side effects.

However, there are some serious side effects to be aware of. If you experience nausea, vomiting, a loss of appetite, unexpected weight loss, or changes in your mental state, it's important to seek medical attention. Additionally, signs of kidney issues like altered urine output, bone or muscle pain, headaches, increased thirst or urination, weakness, fatigue, or a rapid or pounding heartbeat require prompt medical evaluation.

Allergic reactions to this medication are rare but can be severe. If you notice symptoms such as a rash, itching or swelling especially on the face, tongue, or throat, severe dizziness, or difficulty breathing, immediate medical help is necessary.

This list does not cover all possible side effects. If you experience any other unusual symptoms, it is important to consult with a healthcare provider. Remember, while side effects can occur, many individuals benefit from this medication without significant issues.

Some medications that can interact with this product include digoxin and phosphate binders. Calcium has the potential to reduce the absorption of other medications such as tetracycline antibiotics (e.g., doxycycline, minocycline), bisphosphonates (e.g., alendronate), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin). Additionally, some drugs like bile acid sequestrants (e.g., cholestyramine, colestipol), mineral oil, and orlistat can decrease the absorption of vitamin D. To avoid interactions, try to take these medications at different times from your calcium/vitamin D doses. Consult your doctor or pharmacist for advice on how to space out your doses and create a suitable dosing schedule.

Always check the labels on all your prescription, over-the-counter, and herbal products (such as antacids, laxatives, and vitamins) for calcium, phosphate, or vitamin D content, and talk to your pharmacist about safe usage. Avoid using medications that contain calcitriol when taking vitamin D, as they are very similar. Be aware that this product might interfere with certain laboratory tests, like cholesterol tests, potentially leading to incorrect results. Ensure that all your healthcare providers and lab personnel know you are using this product.