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You might experience mild side effects such as drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or a dry sensation in your mouth, nose, or throat. These are generally not serious but should be monitored if they persist or worsen. To alleviate dry mouth, try sugarless candies or gum, ice chips, and stay hydrated. This medication can also make mucus in your lungs thicker, which can complicate breathing and lung clearance; drinking plenty of fluids can help mitigate this effect.

To minimize the risk of dizziness or lightheadedness, it is advisable to rise slowly from sitting or lying positions. Although most people do not experience severe side effects, it is important to be aware of them. Serious side effects requiring immediate medical attention include mental or mood changes like confusion or hallucinations, ringing in the ears, tremors, difficulty urinating, unusual weakness, easy bruising or bleeding, and irregular heartbeat or seizures.

While severe allergic reactions to this medication are rare, they require urgent medical attention. Symptoms include rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, and difficulty breathing. Always consult with your healthcare provider if you notice any side effects or have concerns about your medication.

Certain medications, particularly MAO inhibitors, can interact severely with this drug, potentially leading to serious or even fatal outcomes. You should not take MAO inhibitors such as isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while using this medication. Additionally, it's important to avoid most MAO inhibitors for two weeks before starting and after finishing this treatment. Consult your doctor for guidance on when to begin or cease this medication.

This medication may also interact with certain products, including topical antihistamines (like diphenhydramine cream, ointment, or spray) and rolapitant. Inform your doctor or pharmacist if you are using other substances that induce drowsiness, such as opioid painkillers or cough suppressants (like codeine or hydrocodone), alcohol, cannabis, sleep or anxiety medications (like Alprazolam, Lorazepam, Zolpidem), muscle relaxants (like Carisoprodol, Cyclobenzaprine), or other antihistamines (like Cetirizine, diphenhydramine).

Be vigilant with all your medications, including those for allergies or colds, as they may contain drowsiness-inducing ingredients. Consult your pharmacist to ensure safe usage of these products.

Moreover, this medication might affect certain medical or laboratory tests, such as brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests, potentially leading to inaccurate results. Inform all healthcare providers and lab technicians that you are taking this medication.