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When taking this medication, you might experience some mild side effects such as drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or a dry mouth, nose, or throat. These effects are generally not serious but if they persist or worsen, it is important to contact your healthcare provider. To ease a dry mouth, try sugarless candy, ice chips, gum, drinking water, or saliva substitutes. This medication can also thicken mucus in the lungs, making breathing more difficult, so drinking plenty of fluids can help, unless advised otherwise.

To minimize dizziness or lightheadedness, rise slowly from sitting or lying down. While most people do not experience severe side effects, it's important to be aware of them. Contact your healthcare provider immediately if you notice mental or mood changes like confusion or hallucinations, ringing in the ears, tremors, difficulty urinating, weakness, unusual bruising or bleeding, irregular heartbeat, or seizures.

Allergic reactions to this medication are rare but require immediate medical attention if they occur. Symptoms of a serious allergic reaction include rash, itching or swelling particularly of the face, tongue, or throat, severe dizziness, or trouble breathing. If you experience any other unusual effects, reach out to your healthcare provider for advice.

Certain MAO inhibitors can lead to a severe and potentially life-threatening interaction with this medication. It is important to avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine while using this medicine. Additionally, most MAO inhibitors should not be used for two weeks before and after treatment with this medication. Consult your doctor for guidance on when to begin or discontinue use of this medication.

Some other products that may interact with this drug include skin-applied antihistamines (like diphenhydramine cream, ointment, or spray) and rolapitant. Inform your doctor or pharmacist if you are taking other substances that induce drowsiness, such as opioid pain or cough medications (e.g., codeine, hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety treatments (like alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or additional antihistamines (like cetirizine, diphenhydramine).

Always check medicine labels, including those for allergy or cough-and-cold treatments, as they may have ingredients that cause drowsiness. Your pharmacist can provide advice on using these products safely.

This medication might interfere with certain medical or laboratory tests, such as brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests, potentially leading to incorrect results. Ensure that all lab personnel and healthcare providers are informed about your use of this drug.