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The following information highlights important safety considerations for individuals using Ryaltris (olopatadine / mometasone). It is crucial to understand the potential risks and necessary precautions. Please consult your healthcare provider for any concerns or questions.

• Nasal Problems: Ryaltris may cause nosebleeds, sores, or damage to the nasal tissue, potentially leading to serious injuries to the nasal septum. Notify your healthcare provider if you experience crusting, bleeding, a runny nose, or a whistling sound while breathing. Risks increase with nasal surgery, injury, ulcers, or prolonged use.

• Drowsiness: This medication can cause drowsiness. Until you know how it affects you, avoid driving, operating machinery, or engaging in activities requiring alertness. Refrain from consuming alcohol or using other drowsiness-inducing medications.

• Eye and Vision Problems: Ryaltris can raise eye pressure, possibly leading to glaucoma or cataracts. If you have a history of these conditions, consult your eye care provider before using this medication. Report any vision changes immediately.

• Allergic Reactions: Be aware of potential allergic reactions, such as wheezing, hives, rash, or swelling of the lips or tongue. Seek immediate medical attention if you experience difficulty breathing.

• Risk of Infection: The medication may compromise your immune system, increasing susceptibility to infections like chickenpox and measles. Recovery from infections may be prolonged.

• Altered Stress Hormone Levels: High doses of Ryaltris can impact cortisol levels, causing weight gain or loss, muscle weakness, and other symptoms. Use the medication exactly as prescribed, adhering to the recommended dose and duration.

• Slowed Growth in Children: There is a potential risk of slowed growth in children. To minimize this risk, use the lowest effective dose for the shortest duration. Discuss concerns with your child's pediatrician.

Note that there are no contraindications currently specified for Ryaltris. Always follow your healthcare provider's instructions and report any adverse effects promptly.

When using this medication, some people might experience a bitter taste in the mouth, nosebleeds, or nasal discomfort. These are common side effects and are generally mild, but if they persist or worsen, it is advisable to consult a healthcare provider. Drowsiness can also occur, albeit rarely.

In some cases, more serious side effects may arise, such as pain or sores in the nose, white patches in the nose or mouth, and difficulty swallowing. While these are less common, they should not be ignored. Rarely, corticosteroids administered nasally can enter the bloodstream, potentially leading to symptoms like extreme tiredness, weight loss, headaches, swelling in the ankles or feet, increased thirst or urination, and vision problems. These are more likely in children and those using the medication long-term or in high doses.

A severe allergic reaction is very rare but serious. Symptoms might include rash, itching, swelling, particularly of the face, tongue, or throat, severe dizziness, and difficulty breathing. Immediate medical attention is required if these occur. If you notice any other unusual effects, it is important to contact a healthcare professional.