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Spironolactone

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generic Aldactone, Carospir

Spironolactone, commonly known by its brand name Aldactone, is a potassium-sparing diuretic, often referred to as a "water pill." It is primarily prescribed to help manage heart failure, high blood pressure, and swelling (edema) caused by liver or kidney issues. By reducing high blood pressure, spironolactone aids in lowering the risk of strokes, heart attacks, and kidney complications. It is also effective in treating conditions characterized by excessive production of the hormone aldosterone, such as primary aldosteronism. Spironolactone works by blocking aldosterone, which allows the kidneys to expel excess water and sodium while retaining potassium. This process helps decrease fluid buildup in the blood vessels and other parts of the body, improving symptoms like difficulty breathing associated with fluid retention. The medication is typically taken orally, either once or multiple times daily, depending on individual health needs. Common side effects may include breast tenderness and reduced libido in males. Always consult with a healthcare professional before starting any new medication.
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100MG, Spironolactone (30 Tablets)

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CVS

$20.70

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$9.12

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$9.32

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More prescriptions for aldosteronism

coupons from$8.61Save 80%

More prescriptions for aldosteronism

Aldactone Save 80%coupons from $8.61

Spironolactone dosage forms

The average cost for 30 Tablets of Spironolactone (generic Aldactone, Carospir) at 25MG is $2 with a free coupon. This is 4.83% off the average retail price of $41.4
DosageQuantityPrice fromPer unit
25MG30 Tablets$2$0.07
100MG30 Tablets$8.94$0.3
50MG30 Tablets$4.37$0.15

Spironolactone Warnings

The safety information below outlines important risks and precautions associated with using spironolactone (Aldactone). It is crucial to review these details and discuss any concerns with your healthcare provider.

  • High Blood Potassium Levels: Spironolactone may increase potassium in the blood, posing a serious risk, especially for individuals with kidney disease or those on other potassium-increasing medications. Regular monitoring of potassium levels is essential, particularly a week after starting the medication and periodically thereafter. Symptoms of high potassium include fatigue, muscle weakness, numbness, nausea, or vomiting. Immediate consultation with a healthcare provider is advised if these occur.

  • Dehydration, Low Blood Pressure, and Kidney Issues: This medication increases urine production, potentially causing dehydration, reduced blood pressure, and kidney complications. Individuals with pre-existing kidney issues or those using other kidney-impacting drugs like NSAIDs and certain antibiotics are at higher risk. Regular kidney function tests may be recommended by your healthcare provider.

  • Abnormal Electrolyte Levels: Spironolactone can decrease sodium, calcium, and magnesium levels, vital for various bodily functions. Low levels may result in muscle cramps, fainting, irregular heartbeat, or seizures. Healthcare providers will monitor these electrolytes before and during treatment to ensure safety.

  • Breast Pain or Swelling: Both males and females might experience breast pain or swelling, especially at higher doses. This side effect can manifest within 1-2 months of starting treatment or after longer-term use, often resolving once the medication is discontinued. Discuss alternatives with your healthcare provider if this side effect is problematic.

Contraindications: Spironolactone should not be used under the following conditions due to potential severe health risks. Consult your healthcare provider if any of these apply:

  • Existing high potassium levels
  • Addison's disease
  • Concurrent use of eplerenone (Inspra)

Spironolactone Side Effects

Common side effects:

  • dizziness
  • drowsiness
  • headache
  • nausea
  • vomiting
  • diarrhea
  • stomach upset

Less common but important to monitor:

  • breast pain or enlargement in men
  • lower sex drive
  • menstrual irregularities

Serious side effects:

  • muscle cramps
  • irregular heartbeats
  • confusion
  • changes in urination
  • muscle weakness
  • trouble breathing
  • persistent nausea or vomiting
  • dark urine
  • yellowing of the skin or eyes
  • rash
  • swelling
  • severe dizziness
  • difficulty breathing

Spironolactone Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Interactions with low risk that usually do not require a change in therapy:

  • Digitoxin
  • Licorice
Spironolactone FAQs
What is the drug spironolactone used for?

Spironolactone is primarily used as a diuretic to treat conditions such as heart failure, hypertension, and edema associated with liver cirrhosis or nephrotic syndrome. It is also used to treat hyperaldosteronism and can be prescribed for managing acne and hirsutism in certain cases.

Spironolactone can have several effects on a woman's body. It is primarily used as a diuretic to help reduce fluid retention and treat conditions like hypertension and heart failure. Additionally, it has anti-androgen properties, which means it can help reduce the effects of male hormones. This can be beneficial in treating conditions such as acne, hirsutism (excessive hair growth), and polycystic ovary syndrome (PCOS). It may also help in managing hormonal imbalances. However, it can cause side effects such as menstrual irregularities, breast tenderness, and electrolyte imbalances. It is important for women taking spironolactone to be monitored by their healthcare provider.

While taking spironolactone, one should avoid consuming potassium-rich foods and supplements, as spironolactone can increase potassium levels in the blood, potentially leading to hyperkalemia. Additionally, it's advisable to avoid alcohol, as it can enhance certain side effects like dizziness. It's also important to avoid using other medications that can increase potassium levels, such as certain diuretics and ACE inhibitors, without consulting a healthcare provider.

Spironolactone is not a weight loss pill. It is a medication primarily used as a diuretic and for conditions such as heart failure, hypertension, and certain hormonal disorders. While it may cause some reduction in water weight due to its diuretic effect, it is not intended or prescribed for weight loss purposes.

Spironolactone should not be mixed with potassium supplements or other potassium-sparing diuretics, as this can lead to hyperkalemia, a condition characterized by elevated potassium levels in the blood. Additionally, caution should be exercised when using spironolactone with ACE inhibitors, ARBs, or NSAIDs, as these can also increase the risk of hyperkalemia. It is important to consult with a healthcare provider before combining spironolactone with any other medications.