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The following safety advisories are crucial for understanding the potential risks associated with using riluzole (Rilutek). It is important to review these details and discuss any concerns with your healthcare provider.

• Liver Injury and Damage: Riluzole (Rilutek) can impair liver function and may lead to serious liver damage. Regular blood tests are necessary to monitor liver health before and during treatment. Be vigilant for symptoms such as fever, rash, loss of appetite, abdominal pain, dark urine, or jaundice (yellowing of the skin or eyes). Contact your healthcare provider immediately if these symptoms occur. Individuals with a history of liver disease or those taking other liver-affecting medications should exercise caution.

• Low White Blood Cell Count: Although rare, riluzole (Rilutek) can cause a significant reduction in white blood cell count, which impairs infection-fighting ability. Symptoms to watch for include fatigue, fever, sore throat, or signs of infection. Promptly inform your healthcare provider if these occur.

• Lung Disease: There is a very low risk of developing lung disease while taking riluzole (Rilutek). If you experience a persistent dry cough or difficulty breathing, contact your healthcare provider immediately, as discontinuation of the medication may be necessary. Caution is advised for those with a history of lung disease.

Please ensure to maintain regular consultations with your healthcare provider to discuss these risks and any other concerns you might have.

When using this medication, some common side effects may include dizziness, drowsiness, nausea, vomiting, and numbness or tingling around the mouth. These effects are usually mild, but if they persist or worsen, it is advisable to consult a healthcare provider. Additional common side effects include a feeling of weakness, body fatigue, stomach pain, dry mouth, joint pain, trouble sleeping, and itching. Although these are generally not severe, they should be monitored.

More serious side effects, though rare, require immediate medical attention. These include fast heartbeat, symptoms of liver problems (such as persistent nausea or vomiting, loss of appetite, stomach pain, yellowing of the eyes or skin, and dark urine), and signs of infection like a persistent sore throat or fever. Breathing issues, such as shortness of breath, wheezing, or difficulty catching your breath, are also considered serious. Furthermore, a very serious allergic reaction is rare but warrants urgent care if symptoms like rash, itching or swelling, severe dizziness, or trouble breathing occur.

It's important to be vigilant about changes in your health while on this medication and to contact a healthcare provider if you experience side effects not listed here or if you have any concerns about your reactions to the medication.