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When taking this medication, you might experience mild side effects such as nausea, vomiting, headaches, bloating, breast tenderness, ankle or foot swelling due to fluid retention, or changes in weight. Spotting or irregular periods may occur, especially during the initial months of use. These effects are typically manageable, but if they persist or worsen, consult your healthcare provider.

Be aware that this medication can elevate blood pressure, so regular monitoring is advised. Contact your healthcare provider if you detect any significant increases. Serious side effects, though less common, require immediate attention. These include breast lumps, mood changes like depression, severe abdominal pain, unusual changes in vaginal bleeding, dark urine, or yellowing of the skin or eyes.

In rare instances, this medication can lead to blood clots, which may result in heart attacks, strokes, or clots in the lungs or legs. Seek urgent medical care if you experience symptoms such as chest pain, confusion, sudden dizziness or fainting, severe headaches, swelling or warmth in the groin or calf, trouble speaking, shortness of breath, or vision changes.

Although a severe allergic reaction is rare, it necessitates immediate medical attention. Look out for rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or breathing difficulties. Always communicate with your healthcare provider about any side effects you notice.

Some medications can interact with this drug, including aromatase inhibitors (like anastrozole and exemestane), fezolinetant, ospemifene, tamoxifen, tizanidine, tranexamic acid, and certain combination treatments for chronic hepatitis C (such as ombitasvir/paritaprevir/ritonavir, with or without dasabuvir).

Certain drugs might reduce the effectiveness of hormonal birth control by lowering hormone levels, which could lead to pregnancy. These include griseofulvin, modafinil, rifamycins (such as rifampin and rifabutin), ritonavir, St. John's wort, seizure medications (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, and topiramate), and some HIV treatments (like nelfinavir and nevirapine).

It’s important to inform your doctor when you begin any new medication and discuss whether additional birth control methods are necessary. Report any unusual spotting or breakthrough bleeding to your doctor, as these could indicate that your birth control is less effective.

This drug may also affect certain lab tests, such as those measuring blood clotting factors or thyroid function, potentially leading to incorrect results. Ensure that all healthcare providers and lab personnel are aware that you are taking this medication.