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When taking this medication, you might experience common side effects such as drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth, nose, or throat. These are usually mild and manageable, but if they persist or worsen, consult your healthcare provider. To ease dry mouth, consider using sugarless candy or gum, staying hydrated, or using saliva substitutes. Be mindful that this medication may make mucus in your lungs thicker, which could affect breathing, so it’s advisable to drink plenty of fluids unless instructed otherwise.

To minimize dizziness and lightheadedness, stand up slowly from sitting or lying down. It's important to be aware of more serious side effects, which could include mental or mood changes, such as confusion or hallucinations, ringing in the ears, tremors, difficulty urinating, weakness, unusual bruising or bleeding, and irregular heartbeat. In rare cases, seizures may occur. If you encounter these symptoms, seek medical attention promptly.

Severe allergic reactions are rare but can happen. Look out for signs such as rash, swelling, especially around the face or throat, severe dizziness, or trouble breathing, and seek immediate medical help if they occur. While these are the known side effects, if you observe any other unusual symptoms, it’s best to reach out to your healthcare provider.

Certain medications, specifically MAO inhibitors, can result in a severe and potentially life-threatening interaction with this drug. It is crucial to avoid using isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine while taking this medication. Additionally, most MAO inhibitors should not be taken for at least two weeks before and after your course of this treatment. Consult your healthcare provider for guidance on when to begin or discontinue this medication safely.

This drug may also interact with other products, including skin-applied antihistamines like diphenhydramine cream, ointment, or spray, and rolapitant. Inform your doctor or pharmacist if you are using other substances that induce drowsiness such as opioid pain relievers or cough suppressants (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety medications (e.g., alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or other antihistamines (e.g., cetirizine, diphenhydramine).

Be sure to review the labels of all your medications, including allergy or cough-and-cold products, as they might have components that cause drowsiness. Consult your pharmacist for advice on how to use these products safely.

Lastly, this medication could interfere with certain medical or laboratory tests, such as brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests, possibly leading to inaccurate results. Ensure that all healthcare professionals and lab staff are aware that you are using this medication.