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Antidepressant medications are commonly prescribed to manage depression and other mental or mood disorders. They can significantly help in preventing suicidal thoughts and attempts, along with offering other therapeutic benefits. However, it is crucial to be aware that a small percentage of individuals, particularly those under the age of 25, may experience an increase in depressive symptoms, other mental health issues, or suicidal thoughts and behaviors while taking these medications.

Here are important points to consider:

• Discuss thoroughly with your healthcare provider the potential risks and benefits of using antidepressants, especially if you are under 25 or if the medication is prescribed for conditions other than mental or mood disorders.
• Immediately inform your doctor if you observe any deterioration in depression or psychiatric symptoms, or if you experience any unusual behavioral changes, such as suicidal thoughts or attempts, new or worsening anxiety, panic attacks, sleep disturbances, irritability, hostility, impulsive behavior, severe restlessness, or extremely rapid speech.
• Pay special attention to these symptoms when you begin a new antidepressant or if there is a change in the dosage.

Remaining vigilant for these signs and maintaining open communication with your healthcare provider can aid in managing your treatment safely and effectively.

When taking this medication, you may experience mild side effects such as diarrhea, nausea, vomiting, dizziness, or trouble sleeping. These are common and often not serious, but if they persist or worsen, consult your healthcare provider.

More serious side effects can occur and require immediate medical attention. These include easy bleeding or bruising, numbness or tingling, tremors, inability to remain still, difficulty concentrating, confusion, memory issues, weakness, unsteadiness, and changes in sexual desire or performance.

In rare instances, very serious side effects may arise, such as black stools, vomit resembling coffee grounds, seizures, eye pain or swelling, widened pupils, and vision changes like seeing rainbows around lights.

There is also a risk of serotonin syndrome, a potentially life-threatening condition, especially if you are taking other serotonin-increasing drugs. Symptoms include a rapid heartbeat, hallucinations, loss of coordination, severe dizziness, severe gastrointestinal issues, muscle twitching, unexplained fever, and unusual agitation.

Additionally, though rare, severe allergic reactions can occur. Seek immediate help if you experience a rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing. Always report any side effects you encounter, even if not listed above, to your healthcare provider for advice and proper management.

This medication can interact with several other drugs. If you are taking medications that increase the risk of bleeding or bruising, such as antiplatelet drugs like clopidogrel, NSAIDs like ibuprofen or naproxen, or blood thinners like dabigatran or warfarin, inform your doctor. Aspirin may also raise the bleeding risk when used with this medication. However, if your doctor has advised you to take low-dose aspirin (81-162 milligrams daily) for heart attack or stroke prevention, continue unless directed otherwise by your doctor.

Avoid using MAO inhibitors (e.g., isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) while on this medication, as it may lead to a severe or potentially fatal interaction. Most MAO inhibitors should also be avoided for two weeks before and after taking this medication. Consult your doctor for guidance on starting or stopping these medications.

Additionally, there is an increased risk of serotonin syndrome or toxicity if you are taking other drugs that raise serotonin levels, including MDMA ("ecstasy"), St. John's wort, or certain antidepressants like SSRIs (e.g., fluoxetine, paroxetine) and SNRIs (e.g., duloxetine, venlafaxine), as well as tryptophan. This risk may be higher when starting or increasing the dose of these drugs.

Lastly, this medication might affect the results of certain medical or laboratory tests, such as brain scans for Parkinson's disease, leading to inaccurate results. Ensure that all healthcare providers and lab personnel are aware that you are taking this medication.