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This vaccine is used to help prevent typhoid fever. Typhoid fever is an infection that can be spread by eating contaminated food or drinking contaminated water. This vaccine is recommended for people who are traveling to areas where the infection is common (such as Africa, Asia, Central/South America), those who are in close contact to someone with an ongoing typhoid infection, and those who work with the bacteria (Salmonella typhi) in a lab. This vaccine contains live bacteria that have been weakened. It works by increasing the body's natural defense (immunity) against the bacteria. Vaccines may not fully protect everyone who receives them.