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This medication is used to treat certain types of cancer (such as kidney cancer, pheochromocytoma, paraganglioma). It is also used to treat people with a certain inherited disorder (von Hippel-Lindau disease) who need treatment for tumors/cancers caused by the disease (such as in the kidneys, pancreas, brain/spinal cord). Belzutifan works by slowing or stopping the growth of cancer/tumor cells.