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Bupropion is a medication primarily used as an antidepressant and to aid in smoking cessation. It is effective for treating conditions like depression and other mental health disorders. While antidepressants offer significant benefits, including the prevention of suicidal thoughts and behaviors, a small percentage of individuals—particularly those under 25—may experience worsening depression, new mental health symptoms, or suicidal thoughts when taking these medications.

Key Safety Information:

• Discuss the potential risks and benefits of using antidepressants with your healthcare provider, even if you are not being treated for a mental/mood disorder.
• Immediately inform your doctor if you observe any new or worsening symptoms of depression, changes in mental health, or unusual behavior, such as suicidal thoughts, increased anxiety, panic attacks, sleep disturbances, irritability, hostility, impulsive actions, severe restlessness, or rapid speech.
• Pay close attention to these symptoms when starting bupropion or adjusting the dosage.
• If you are using bupropion to help quit smoking and notice any of these adverse effects, discontinue use and contact your healthcare provider promptly.
• Report any of the aforementioned symptoms to your doctor, even if they occur after you have stopped taking bupropion.

This information is critical for ensuring safe and effective use of bupropion, particularly for those with a heightened risk of adverse reactions.

This medication can cause some common side effects, including dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, and shaking (tremor). These effects are usually mild, but if they persist or worsen, it is important to seek advice from a healthcare professional. Additionally, you might notice an empty tablet shell in your stool, which is harmless as the medication has already been absorbed by your body.

It is important to monitor your blood pressure while using this medication, as it may cause an increase. If you experience significant changes in your blood pressure, consult a healthcare provider. Be vigilant for serious side effects such as a fast, pounding, or irregular heartbeat, changes in mental state (including anxiety, agitation, confusion, unusual behavior, or memory loss), and unusual weight changes. Seek immediate medical attention if these occur.

Very serious side effects, although rare, require urgent medical help. These include seizures, eye pain, swelling, redness, widened pupils, and vision changes like seeing rainbows around lights or blurred vision. Allergic reactions to this drug are uncommon, but if you experience symptoms like rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, get medical help right away. Always consult a healthcare professional if you notice any other unusual effects.