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The safety information outlined below is crucial for understanding the potential risks and precautions associated with using AirDuo (fluticasone/salmeterol). Patients are encouraged to carefully review these warnings and consult their healthcare provider with any concerns.

• Asthma Attack Use: AirDuo is not suitable for treating an asthma attack or sudden worsening of breathing issues. For immediate relief, use a rescue inhaler like albuterol.

• Mouth Fungal Infections: There's a risk of developing thrush, a fungal infection in the mouth and throat, especially if you do not rinse and spit after using AirDuo. This risk is higher for those with weakened immune systems. Symptoms include white patches, a cotton-like feeling, pain while swallowing, and loss of taste. Inform your provider if these occur.

• Bronchospasm Risk: Inhaled medications, including AirDuo, might cause bronchospasm, leading to breathing difficulties, wheezing, or chest discomfort. Use a rescue inhaler if these symptoms occur and seek medical attention immediately.

• Infection Risk: As a corticosteroid, AirDuo can weaken the immune system, increasing the risk of infections like upper respiratory infections or pneumonia. This risk is elevated if you're taking other immune-weakening medications. Notify your provider if you experience symptoms like fever or body aches.

• Hormone Level Alterations: Using AirDuo in excess can lead to increased absorption of steroids, potentially affecting blood sugar and pressure levels. Use only as directed to mitigate these risks.

• Growth in Children: Inhaled steroids can delay growth in children. Providers will prescribe the minimum effective dose and regularly monitor growth. Discuss any concerns with your child's healthcare provider.

• Eye Health Concerns: Prolonged use of inhaled steroids may increase the risk of eye problems like glaucoma or cataracts. Regular eye exams are advised, especially if you have a history of these conditions.

• Heart-related Issues: AirDuo may affect blood pressure, heart rate, and rhythm, especially if used in excess. Regular monitoring is recommended for patients with pre-existing heart conditions. Report symptoms like dizziness or a rapid heartbeat to your provider.

• Potassium Levels: Excessive use of AirDuo can lower potassium levels, potentially causing tiredness, muscle cramps, or a "pins and needles" sensation. Inform your provider if these symptoms arise.

• Allergic Reactions: Some individuals may experience severe allergic reactions, including swelling, rash, or anaphylaxis. Seek immediate medical assistance if any of these occur.

Contraindications:

• Do not use AirDuo for sudden, severe asthma attacks.
• Avoid if allergic to fluticasone, salmeterol, lactose, or milk proteins.

Always discuss your health conditions and any medications you are taking with your healthcare provider to ensure AirDuo is safe and effective for your treatment plan.

Common side effects:

• Runny nose
• Sore throat
• Headaches

Less common but important to monitor:

• Cough
• Back pain
• Oral thrush

Serious side effects:

• Serious allergic reaction
• Hives
• Swelling of the face, lips, or tongue
• Difficulty breathing
• Sudden narrowing of the airways
• Wheezing
• Chest pain
• Tightness
• Heart-related issues
• Dizziness
• Fatigue
• Tremor
• Nausea
• Rapid heartbeat
• Weakness
• Difficulty sleeping