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You may experience drowsiness, dry mouth, or tiredness while taking this medication. These effects are usually mild and manageable, but if they persist or worsen, it's important to consult with a healthcare professional. To alleviate dry mouth, consider using sugarless hard candy or ice chips, chewing sugarless gum, drinking water, or trying a saliva substitute.

While most people do not experience serious side effects from this medication, it's crucial to be aware of them. Contact a healthcare provider immediately if you notice mental or mood changes, such as restlessness or confusion, a fast or irregular heartbeat, tremors, or difficulty urinating. These symptoms could indicate more severe side effects.

In rare cases, very serious side effects can occur. Seek urgent medical attention if you experience seizures or signs of a severe allergic reaction, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. While these reactions are rare, they require immediate care.

This information covers the most common and serious side effects, but it's not exhaustive. If you experience any other unusual effects, it's advisable to seek guidance from a healthcare provider.

Certain products may interact with this medication, including topical antihistamines like diphenhydramine creams, ointments, or sprays. Inform your doctor or pharmacist if you are using other substances that can cause drowsiness. These may include opioid pain or cough medications (such as codeine or hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (such as alprazolam, lorazepam, or zolpidem), muscle relaxants (like carisoprodol or cyclobenzaprine), and other antihistamines (such as cetirizine or diphenhydramine).

It's important to check the labels of all your medications, including allergy or cough-and-cold products, as they might contain ingredients that induce drowsiness. Consult your pharmacist for advice on safely using such products.

Additionally, this medication may affect certain laboratory tests, including allergy skin tests, potentially leading to inaccurate results. Ensure that all healthcare professionals and lab staff are aware of your medication use.