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This safety information outlines critical warnings associated with the use of Tigan (trimethobenzamide). It's essential to review these points and discuss any concerns with your healthcare provider.

• Movement Disorders: Tigan may lead to sudden muscle spasms, particularly in the head and neck, and Parkinson-like symptoms such as tremors. It may also cause restlessness and difficulties with swallowing or speaking. If these symptoms occur, contact your healthcare provider immediately. They may adjust your dosage or recommend discontinuing the medication. Note that this risk increases if you are taking other medications that can cause movement issues.

• Cognitive Impairment: This medication can induce drowsiness and impact your cognitive abilities, affecting your safety while driving or operating machinery. Some individuals may experience depression, confusion, seizures, or even comas. Alert your healthcare provider if you notice mood or behavioral changes. Inform family members or caregivers about these risks so they can assist you in seeking help if necessary. The risk is elevated when Tigan is combined with sedatives, alcohol, opioids, or anticholinergics.

• Masking Underlying Conditions: The side effects of Tigan, such as movement and cognitive issues, might obscure more serious health conditions. Notify your healthcare provider if you experience changes in movement, mood, or behavior, as a thorough examination is needed to rule out other potential health problems.

• Liver Health: Tigan may be detrimental to liver health. Your provider may require blood tests before starting the medication to ensure there is no existing liver damage. Seek immediate medical attention if you experience jaundice, abdominal pain, or dark urine. This risk is particularly concerning for those with a history of liver issues.

There are currently no known contraindications for Tigan. Always consult your healthcare provider to ensure this medication is safe for you, especially if you have pre-existing health conditions or are taking other substances.

When taking this medication, some common side effects might include headache, dizziness, drowsiness, blurred vision, muscle cramps, and diarrhea. These effects are generally mild, but if they persist or worsen, it is advisable to consult with a healthcare provider for reassurance and guidance. Additionally, some individuals may experience confusion, tremors, or a rash. While these are not typically alarming, monitoring these symptoms is important.

However, there are more concerning side effects that require immediate medical attention. These include significant mental or mood changes such as depression, severe muscle spasms, uncontrollable movements, restlessness, yellowing of the eyes or skin, dark urine, and mouth sores. Such symptoms may indicate more serious conditions like liver damage or changes in brain function.

In rare instances, a severe allergic reaction may occur, marked by rash, severe dizziness, swelling (particularly of the face, tongue, or throat), and trouble breathing. If these symptoms arise, seeking emergency medical assistance is crucial. Although severe side effects are uncommon, being aware and vigilant about these possibilities ensures safe use of the medication.

When using Tigan (trimethobenzamide), it's important to inform your doctor or pharmacist about all other medications or supplements you are taking, whether they are prescription, over-the-counter, vitamins, or herbal products. This is because Tigan can interact with certain drugs, potentially causing unwanted effects.

Be cautious when combining Tigan with products that induce drowsiness, such as opioid pain relievers (like codeine or hydrocodone), alcohol, marijuana, sleep or anxiety medications (such as alprazolam, lorazepam, or zolpidem), muscle relaxants (such as carisoprodol or cyclobenzaprine), and antihistamines (such as cetirizine or diphenhydramine). Always check the labels of all your medications, particularly those used for allergies or cold and cough, as they may contain ingredients that cause drowsiness. Consult your pharmacist to ensure safe usage.

Additionally, using Tigan with certain medications like Bromopride is generally not advised. In cases where using Tigan with medications such as Quetiapine is necessary, your doctor may need to adjust the dosage or frequency to reduce the risk of interactions. Always follow your healthcare provider's guidance when taking Tigan with other medications.