Aprepitant

Drug Details

Aprepitant is a medication designed to prevent nausea and vomiting associated with cancer treatments, specifically chemotherapy. It is typically used alongside dexamethasone and a serotonin antagonist like ondansetron (Zofran) to enhance its effectiveness. Aprepitant acts as an antiemetic by blocking the NK1 receptors in the brain, which are responsible for triggering nausea and vomiting. This medication is available in capsule form for individuals aged 12 and older and as an oral solution for adults who have difficulty swallowing and for younger children. It is administered before chemotherapy sessions over a period of three days. While aprepitant is effective in preventing nausea and vomiting, it does not treat these symptoms once they have begun. Common side effects include fatigue and diarrhea. Always consult with your healthcare provider before starting this medication to ensure it is safe and appropriate for your condition.