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It is important to be informed about the safety details and warnings associated with Emend (aprepitant), especially if you are about to start a chemotherapy cycle. Here are some key points to ensure safe usage:

• Drug Interactions: Before commencing Emend at the start of each chemotherapy cycle, inform your healthcare provider about all medications, vitamins, and supplements you are currently taking. This allows them to identify and prevent any potentially serious interactions with Emend.

• Contraindications: Emend should not be taken if you are currently using pimozide, a medication prescribed for Tourette syndrome. Doing so may lead to serious health risks. Consult your healthcare provider for guidance if this applies to you.

Always discuss any concerns or questions with your healthcare provider to ensure safe and effective use of Emend.

When taking this medication, some common side effects may include tiredness, diarrhea, weakness, indigestion, belly pain, and hiccups. These symptoms are generally mild and may subside as your body adjusts to the medication. However, if they persist or worsen, it is advisable to consult your healthcare provider for further guidance.

Additional side effects that have been reported include a lower white blood cell count, headache, low appetite, cough, dizziness, and a lower red blood cell count. While these effects may occur in some individuals, they are not experienced by everyone. Monitoring your health and discussing any concerns with your healthcare provider can help manage these symptoms effectively.

In rare cases, more serious side effects may occur, such as dehydration and changes in liver function tests. These require immediate medical attention due to their severity. It is crucial to seek urgent care if you experience symptoms indicative of these conditions.

An allergic reaction to this medication is highly uncommon but should be taken seriously. Symptoms such as rash, itching or swelling, severe dizziness, and trouble breathing necessitate prompt medical intervention. Always stay informed about your health and communicate any unusual symptoms to your healthcare provider to ensure a safe and effective treatment experience.

Aprepitant, also known as Emend, can interact with a variety of medications, which may alter its effectiveness or the effectiveness of the other drugs. It is important to inform your doctor and pharmacist about all medications and supplements you are currently taking. Here are some key interactions to be aware of:

1. Significant Interactions: Aprepitant should not be used with certain medications, including Eliglustat, Flibanserin, Lomitapide, and Pimozide, as these combinations are not recommended.

2. Medications Requiring Caution: If used with drugs such as Acalabrutinib, Alprazolam, Amiodarone, Atazanavir, Clarithromycin, Diltiazem, Erythromycin, Itraconazole, Ketoconazole, Ritonavir, St. John's Wort, and others, adjustments in dosage or frequency may be necessary due to potential interactions.

3. Hormonal Birth Control: Aprepitant may reduce the effectiveness of hormonal birth control methods like pills, patches, or rings, increasing the risk of pregnancy. It is advisable to use a backup method of contraception during treatment and for one month after the last dose.

4. Blood Thinning Medication: For patients taking warfarin, aprepitant may affect how well the blood thinner works. Blood tests are recommended within the two weeks following aprepitant treatment to ensure proper warfarin function.

5. Similar Medications: Aprepitant is comparable to fosaprepitant, and these medications should not be used together.

Always consult with your healthcare provider to manage and adjust your medications safely.