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The use of irbesartan (Avapro) carries specific risks and precautions that you should be aware of. Below are the key safety warnings and guidelines to follow:

• Risk to Unborn Babies: Using this medication during pregnancy, especially in the second and third trimesters, can harm an unborn baby, potentially causing serious birth defects or even being fatal. If you are pregnant, planning to become pregnant, or suspect you might be pregnant, consult your healthcare provider immediately to consider safer alternatives. Stop taking the medication if you discover you are pregnant and inform your provider right away.

• Low Blood Pressure: Irbesartan can occasionally cause your blood pressure to drop excessively, leading to dizziness, fatigue, or lightheadedness. To prevent these symptoms, stay hydrated and avoid sudden changes in posture, such as quickly standing up from sitting or lying down. If you frequently experience these symptoms, contact your healthcare provider. Risks include dehydration, low salt levels, being on dialysis, or prolonged use of diuretics.

• Kidney Issues: While irbesartan is generally beneficial for kidney function in individuals with high blood pressure or chronic kidney disease, it can, in some cases, worsen kidney problems. The risk increases if you have conditions like blocked kidney arteries or severe heart failure. Your provider might conduct lab tests to monitor your kidney health during treatment. Look out for symptoms like reduced urination, fatigue, nausea, or chills, and inform your provider if these occur.

• High Potassium Levels: Rarely, this medication can elevate potassium levels, which could be hazardous. Your risk is higher if you have diabetes, existing kidney problems, or are taking other potassium-increasing medications. Ensure your provider is aware of your complete medical history and current medications. Report symptoms like nausea, muscle weakness, or irregular heartbeat to your provider immediately.

• Contraindications: Avoid using irbesartan if you are taking aliskiren (Tekturna) and have diabetes, as this combination can lead to severe health complications. Discuss with your healthcare provider if this applies to you before starting the medication.

Always discuss your medical history and any concerns with your healthcare provider to ensure the safe use of irbesartan (Avapro).

When taking this medication, you may commonly experience mild side effects like dizziness, lightheadedness, or an upset stomach as your body adjusts. These effects are typically temporary. To minimize dizziness, try getting up slowly from sitting or lying down. Other common side effects include low blood pressure when standing, fatigue, diarrhea, and heartburn. If these symptoms persist or worsen, consult your healthcare provider for advice.

While many people do not face serious side effects, it is important to be aware of them. Serious side effects that require immediate medical attention include fainting, symptoms of high potassium levels like muscle weakness or an irregular heartbeat, and signs of kidney problems such as changes in urination. Rarely, this medication can cause severe kidney issues or exacerbate existing conditions, so monitoring kidney function is crucial.

Allergic reactions to this medication are rare but can be serious. Seek urgent medical help if you experience symptoms such as a rash, itching, swelling, severe dizziness, or trouble breathing. Additionally, be on the lookout for signs of angioedema, which includes severe swelling of the face, arms, legs, lips, tongue, or throat. If you notice any other unusual effects, even if they seem minor, it is always best to discuss them with your healthcare provider.

When taking Irbesartan (Avapro), it's important to be aware of potential interactions with other medications and supplements. Inform your doctor and pharmacist about all the substances you're currently using, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Certain drugs should not be combined with Irbesartan. For instance, the use of Aliskiren is not recommended. Your doctor might decide to avoid this combination altogether or adjust your medications accordingly.

There are some medications that, while usually not recommended to be taken with Irbesartan, may be necessary in specific situations. These include Benazepril, Lisinopril, and Lithium, among others. If prescribed together, your healthcare provider may alter the dosage or frequency of one or both medications to minimize risks.

Additionally, combining Irbesartan with certain nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen or Naproxen may increase the risk of side effects. However, sometimes this combination is the most effective treatment option. Your doctor may need to adjust how you take these medications to ensure safe and effective use.

Always discuss with your healthcare team before making any changes to how you take your medications.