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This document provides essential safety and warning information about the use of this medication. It is important to read these points carefully and discuss any questions or concerns with your healthcare provider.

• Contamination Prevention: Ensure that the dropper tip of bepotastine (Bepreve) does not come into contact with your eyes, hands, or any surface. Close the bottle immediately after use to prevent contamination and reduce the risk of eye infections caused by germs or bacteria.

• Contact Lens Advisory: The preservative benzalkonium chloride found in bepotastine (Bepreve) can be absorbed by soft contact lenses, potentially causing damage. If you wear soft contact lenses, remove them prior to application and wait at least 10 minutes after using the drops before reinserting them. Avoid wearing contact lenses if your eyes are red, and do not use bepotastine (Bepreve) to address eye irritation stemming from contact lens use.

• Contraindications: Do not use this medication if you are allergic to bepotastine (Bepreve). If you suspect an allergy, consult your healthcare provider before using this medication to prevent serious health risks.

Common side effects:

• Unpleasant taste in the mouth
• Headache
• Eye irritation
• Symptoms similar to a common cold

Serious side effects:

• Severe allergic reaction
• Rash
• Itching or swelling, particularly of the face, tongue, or throat
• Dizziness
• Trouble breathing

Bepotastine is an antihistamine commonly used to treat itchy eyes caused by allergic conjunctivitis. When administered as eye drops, bepotastine has minimal systemic absorption, which reduces the likelihood of interactions with other medications. Currently, there are no well-documented drug interactions associated with bepotastine eye drops.

However, when bepotastine is taken orally, certain interactions may occur. For instance, medications like amphetamine, Dextroamphetamine, and pseudoephedrine may decrease the sedative effects of bepotastine. Additionally, bepotastine may reduce the effectiveness of diagnostic agents such as benzylpenicilloyl polylysine.

It's important to note that bepotastine is minimally metabolized by liver enzymes and is primarily excreted unchanged in the urine. This characteristic further reduces the potential for significant drug interactions.

While no significant interactions are known, it's always advisable to inform your healthcare provider about all medications and supplements you are currently taking before starting bepotastine. This ensures safe and effective use of the medication.