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Please pay careful attention to the following safety information regarding the use of Verapamil ER (Verelan). It is crucial to discuss any concerns with your healthcare provider to ensure safe usage.

• Heart Failure: This medication may lead to heart failure and fluid accumulation in the lungs. If you have a history of heart disease, inform your healthcare provider before starting Verapamil ER. Additional medications, like diuretics, might be necessary. Watch for symptoms such as shortness of breath, fatigue, swelling in the feet, legs, or abdomen, rapid weight increase, dizziness, and coughing. Individuals with a history of heart disease are at higher risk.

• Low Blood Pressure: Verapamil ER can cause a significant drop in blood pressure, although this is uncommon in those with hypertension. Alert your healthcare provider if you experience symptoms like dizziness, lightheadedness, fatigue, blurred vision, dehydration, sweating, cold or pale skin, rapid breathing, or confusion. Those with a history of low blood pressure or who are on blood pressure medications should be particularly cautious.

• Liver Problems: This medication may elevate liver protein levels, which are monitored through blood tests. While some elevations are harmless, others may indicate serious liver issues. If you have liver disease, routine blood monitoring may be required. Notify your provider immediately if you observe yellowing of the skin or eyes, abdominal pain or swelling, loss of appetite, dark urine, nausea, vomiting, fatigue, or confusion. These symptoms could signal liver damage. The risk is higher for individuals with a history of liver disease.

• Heart Rhythm Issues: Verapamil ER can alter heart rhythm, potentially lowering heart rate or causing a serious condition known as heart block. Emergency medical attention is necessary if you experience chest pain, dizziness, shortness of breath, severe fatigue, fainting, or irregular heartbeats. Those taking other blood pressure medications, like beta-blockers, should be aware of these risks.

• Specific Heart Rhythm Conditions: Ensure your healthcare provider is informed of any heart-related conditions, particularly if you have Wolff-Parkinson-White or Lown-Ganong-Levine syndrome, hypertrophic cardiomyopathy, or if you are receiving verapamil by injection.

Contraindications: Verapamil ER should not be used under the following conditions due to serious health risks. Consult your healthcare provider if any of these apply:

• Left ventricular dysfunction
• Systolic blood pressure below 90 mmHg or cardiogenic shock
• Sick sinus syndrome
• 2nd- or 3rd-degree heart block
• Irregular heart rate combined with congenital heart muscle tissue anomalies, such as Wolff-Parkinson-White or Lown-Ganong-Levine syndrome.

It is essential to adhere to these guidelines to minimize the risk of serious complications while using Verapamil ER (Verelan).

When taking this medication, you might experience some common side effects such as dizziness, constipation, nausea, headache, or tiredness. These effects are generally mild and often manageable, but if they persist or worsen, it's important to consult your healthcare provider. To reduce dizziness or lightheadedness, try to rise slowly from sitting or lying positions.

While many people do not encounter serious side effects, it's crucial to be aware of more severe reactions that require immediate medical attention. These include severe dizziness, fainting, new or worsening symptoms of heart failure like shortness of breath, swelling of the ankles or feet, unusual tiredness, or sudden weight gain. A very slow heartbeat is also a cause for concern.

In rare cases, this medication can cause significant liver issues. Seek urgent medical help if you experience persistent nausea or vomiting, loss of appetite, stomach pain, yellowing of the eyes or skin, or dark urine, as these may indicate liver damage. Additionally, a serious allergic reaction, though rare, requires immediate medical attention if you notice symptoms like rash, itching, swelling, severe dizziness, or trouble breathing.

Remember, while these side effects can seem daunting, many individuals take this medication without experiencing serious issues. Always communicate with your healthcare provider if you have any concerns or notice any effects not listed here.

When taking Verapamil, it is important to be aware of potential interactions with other medications. Some drugs can alter how Verapamil is processed in your body, affecting its effectiveness. For instance, Erythromycin, Rifampin, Ritonavir, and St. John's Wort can impact Verapamil's removal from your system.

Furthermore, Verapamil can influence the breakdown and elimination of other drugs, possibly changing their effects. Medications that may be affected include [Colchicine](https://savehealth.com/colchicine), Flibanserin, lomitapide, and Midazolam, among others.

There are certain medications that should generally not be taken with Verapamil, such as Dofetilide, eliglustat, and colchicine, due to the risk of severe interactions. In some cases, your doctor might adjust the dose if it’s necessary to use both.

Additionally, some drugs may raise the risk of side effects when combined with Verapamil, but might still be necessary for your treatment. These include Lithium, Cyclosporine, and certain blood thinners like apixaban. Your healthcare provider may need to adjust dosages or monitor you closely.

Always inform your doctor and pharmacist about all the medications and supplements you are taking to manage your treatment safely and effectively.