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Cathflo Activase is used to restore function to central venous access devices that have become occluded due to blood clots. It is a thrombolytic agent that helps dissolve the clots, allowing the device to function properly again.

Cathflo (alteplase) should not be used in patients with known hypersensitivity to alteplase or any component of the formulation. It is also contraindicated in patients with active internal bleeding, recent intracranial or intraspinal surgery or trauma, or in those with a history of intracranial hemorrhage. Additionally, it should not be used in patients with severe uncontrolled hypertension or in situations where the risk of bleeding outweighs the potential benefits. Always consult a healthcare professional before use to ensure it is appropriate for the patient's specific condition.

It is unsafe to use Cathflo (alteplase) in patients with known hypersensitivity to alteplase or any component of the formulation. Additionally, it should not be used in patients with active internal bleeding or those with a history of intracranial hemorrhage. Caution is advised in patients with recent major surgery, trauma, or severe uncontrolled hypertension. It is important to evaluate the patient's medical history and current condition before administration.

Cathflo Activase works by dissolving blood clots that may be obstructing catheters. It contains alteplase, a tissue plasminogen activator, which helps convert plasminogen to plasmin, an enzyme that breaks down fibrin, the main component of blood clots. This action helps restore the patency of the catheter, allowing for proper function.

Cathflo, also known as alteplase, should be administered by healthcare professionals who are trained and qualified to handle thrombolytic agents. This typically includes doctors, nurses, or other medical personnel who have received specific training in the administration of this medication. It is important that it is administered in a clinical setting where the patient can be monitored for any potential adverse reactions.