Cefazolin

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Cefazolin is a cephalosporin antibiotic used to treat a variety of bacterial infections, including those affecting the respiratory tract, urinary tract, skin, liver, gallbladder, bones, joints, genitals, bloodstream, and heart. It is also used to prevent infections before and during surgery. Cefazolin works by stopping the growth of bacteria, effectively killing them by preventing them from forming their protective cell wall. This medication is administered through an injection, either intravenously (IV) or intramuscularly (IM), and can be used for both adults and children over one month old. While side effects are uncommon, individuals allergic to penicillins or other cephalosporins should avoid using cefazolin. Always consult a healthcare provider before starting any new medication.
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100GM, Cefazolin (30 Solution Reconstituteds)

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CVS

$3560.40

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$3717.81

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$3728.80

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Cefazolin dosage forms

The average cost for 30 Solution Reconstituteds of Cefazolin at 1GM is $18.38 with a free coupon. This is 0.14% off the average retail price of $12910.45
DosageQuantityPrice fromPer unit
1GM30 Solution Reconstituteds$18.38$0.61
10GM30 Solution Reconstituteds$101.43$3.38
500MG30 Solution Reconstituteds$12.98$0.43
100GM30 Solution Reconstituteds$3560.4$118.68
300GM30 Solution Reconstituteds$10350$345
2GM30 Solution Reconstituteds$170.7$5.69

Cefazolin Warnings

The following safety and warning information is crucial for understanding the risks and precautions associated with the use of cefazolin (Ancef). It is essential to thoroughly review this information and discuss any concerns with your healthcare provider.

  • Allergic Reactions: Inform your healthcare provider if you have previously experienced allergic reactions to penicillin-type or cephalosporin antibiotics, as cefazolin (Ancef) can trigger similar allergic responses. If an allergic reaction occurs, such as difficulty breathing or swelling of the face and neck, seek immediate medical attention. Individuals with a history of such allergies may need alternative antibiotics.

  • C. difficile Infection Risk: Use of cefazolin (Ancef) may, in rare cases, lead to a severe bacterial infection that causes intense diarrhea, known as a Clostridioides difficile (C. diff) infection. Risks are heightened by prolonged antibiotic use, recent antibiotic treatment, or existing stomach issues.

  • Development of Drug-Resistant Bacteria: Cefazolin (Ancef) should only be used for treating bacterial infections. Misuse or overuse can result in drug-resistant bacterial infections, which are more challenging to treat. Notify your healthcare provider if you develop new symptoms or if existing symptoms persist. Risks are associated with using cefazolin (Ancef) for non-bacterial infections or for extended periods.

  • Kidney Health Considerations: Cefazolin (Ancef) is eliminated by the kidneys, and impaired kidney function can lead to drug accumulation, increasing the risk of side effects like seizures. Patients with kidney problems or older adults may require dosage adjustments based on kidney function tests. Ensure your healthcare provider is informed about any kidney-related health issues.

  • Contraindications: Do not use cefazolin (Ancef) if you have an allergy to cephalosporin antibiotics, as it may lead to serious health complications. Always consult with your healthcare provider before starting this medication if this condition applies to you.

By understanding these risks and taking necessary precautions, you can use cefazolin (Ancef) safely and effectively.

Cefazolin Side Effects

Common side effects:

  • mild swelling at the injection site
  • redness at the injection site
  • pain at the injection site
  • soreness at the injection site
  • loss of appetite
  • nausea
  • vomiting
  • diarrhea
  • headaches
  • stomach cramps

Less common but important to monitor:

  • oral thrush
  • new vaginal yeast infection
  • mild itching
  • rash

Serious side effects:

  • dark urine
  • easy bruising or bleeding
  • fast or irregular heartbeat
  • seizures
  • unusual weakness
  • yellowing of the eyes or skin
  • mental changes like confusion
  • persistent diarrhea
  • severe stomach pain
  • blood or mucus in stools
  • serious allergic reaction
  • severe dizziness
  • trouble breathing

Cefazolin Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • Cholera Vaccine, Live

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Cefazolin FAQs
What is the drug cefazolin used for?

Cefazolin is an antibiotic used to treat a variety of bacterial infections. It is commonly used for infections of the skin, bone, joint, respiratory tract, urinary tract, and for surgical prophylaxis to prevent infections.

Cefazolin and Keflex are not the same. Cefazolin is a first-generation cephalosporin antibiotic typically administered intravenously or intramuscularly, while Keflex, which is the brand name for cephalexin, is also a first-generation cephalosporin but is taken orally. Both are used to treat bacterial infections, but they differ in their administration routes and specific uses.

Cefazolin and Rocephin are not the same. Cefazolin is a first-generation cephalosporin antibiotic, while Rocephin, which is the brand name for ceftriaxone, is a third-generation cephalosporin. They are used to treat different types of bacterial infections and have different spectrums of activity.

Cefazolin is primarily administered intravenously (IV) or intramuscularly (IM). It is not available in an oral form.

If a person is allergic to Keflex (cephalexin), which is a cephalosporin antibiotic, there is a potential risk of cross-reactivity with cefazolin, another cephalosporin. It is important for the individual to consult with a healthcare provider before taking cefazolin, as they can assess the severity of the allergy and determine the safest course of action.