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This document outlines critical safety information regarding the use of loratadine (Claritin). It is important to understand the potential risks and precautions when taking this medication. If you have any questions or concerns, please discuss them with your healthcare provider.

• Drowsiness Risk: Loratadine may cause drowsiness, impacting your concentration and reaction times. This effect can be intensified by consuming alcohol or using other medications that induce sleepiness, such as opioids, certain anxiety medications, and sleep aids. Avoid driving or operating heavy machinery until you know how loratadine affects you.

• Overdose Warning: Loratadine, like other antihistamines, is present in various over-the-counter products. Using more than the recommended dosage or combining products containing antihistamines, including topical forms, can result in an overdose. Symptoms of overdose may include seizures, hallucinations, or even death. It is crucial to adhere to recommended dosages.

• Phenylketonuria (PKU) Precaution: Some formulations, such as chewable or orally disintegrating tablets, may contain phenylalanine from aspartame. Individuals with PKU should verify the presence of phenylalanine in their loratadine product labels. Consult your pharmacist if uncertain about the suitability of a particular loratadine formulation for your condition, as there are safer alternatives available.

Please follow these guidelines to ensure safe use of loratadine and consult your healthcare provider with any questions.

When using this medication, some individuals may experience common side effects that are generally mild and not cause for concern. These include headaches, which occur in about 12% of users, sleepiness in 8%, fatigue in 4%, and dry mouth in 3%. If these effects persist or become bothersome, consulting a healthcare provider is advisable.

In addition to common side effects, there are other possible reactions, such as dizziness, cough, and sore throat. While these are less frequently reported, it's important to monitor their severity. If any of these symptoms become pronounced, reaching out to a healthcare professional is recommended.

Although very rare, serious side effects can occur and should be treated with urgency. These include symptoms of an allergic reaction like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, and trouble breathing. Additionally, accidentally taking too much of the medication can lead to a fast heartbeat, flushing, extreme sleepiness, changes in vision, and irritability in children. Immediate medical attention is essential in such cases. Always remain vigilant for any unusual effects and seek advice from a healthcare provider if necessary.