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This medication includes important safety warnings that should be carefully considered. Consult your healthcare provider if you have any concerns or questions.

• Accidental Overdose: Be cautious not to use multiple products containing diphenhydramine, the active ingredient in Benadryl, simultaneously. An overdose may cause symptoms such as dry eyes or mouth, rapid heartbeat, difficulty urinating, fever, and constipation. More severe effects include confusion, seizures, low blood pressure, muscle spasms, hallucinations, and heart rhythm disturbances. Ensure that you are not taking other diphenhydramine-containing products concurrently.

• Excessive Sleepiness: This medication can cause significant drowsiness, impacting concentration, thinking, and reaction times. This is especially concerning for older individuals (65 years and above) due to an increased risk of falls and prolonged drowsiness into the following day. The sedative effect can be intensified by alcohol or other drowsiness-inducing medications such as opioids, benzodiazepines, or sleep aids. Refrain from driving or operating heavy machinery until you know how this medication affects you.

• Worsening of Certain Health Conditions: Prior to using diphenhydramine (Benadryl), discuss with your healthcare provider if you have any of the following conditions: glaucoma, enlarged prostate, breathing issues such as emphysema, or kidney problems. The use of this medication can exacerbate these conditions and may lead to serious side effects.

There are no specific contraindications listed for this medication. However, always consult with your healthcare provider to ensure safe use.

When taking this medication, some individuals may experience common side effects such as drowsiness, dizziness, headache, dry mouth, nose, and throat, constipation, and blurred vision. These effects are usually mild and may subside over time. However, if they persist or worsen, it's advisable to consult with a healthcare provider. Simple remedies like staying hydrated or using saliva substitutes can help alleviate dryness of the mouth.

There are other side effects that some people might encounter, including nausea, vomiting, loss of appetite, muscle weakness, nervousness, and hyperactivity, particularly in children. Additionally, difficulty urinating might also be experienced. If any of these symptoms occur, especially if they seem severe, contacting a healthcare provider is recommended.

Serious side effects, while rare, demand immediate medical attention. These include mental or mood changes such as restlessness or confusion, seizures, irregular heartbeat, and severe allergic reactions characterized by rash, itching, swelling, or trouble breathing. Sudden eye pain, changes in vision, or difficulty passing urine are also critical and require urgent care. Although these severe side effects are uncommon, being aware of them ensures prompt action should they arise. Always stay informed about your health and consult a healthcare provider if you notice any unusual symptoms.