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This safety information is crucial for understanding the risks and precautions associated with the use of Combivent Respimat (ipratropium/albuterol). Please read carefully and discuss any concerns with your healthcare provider.

• Bronchospasm Risk: Although rare, Combivent Respimat may cause a muscle spasm in the lungs, leading to breathing difficulties, wheezing, cough, and chest discomfort. If you experience sudden shortness of breath after using the medication, seek medical attention immediately.

• Cardiovascular Effects: There is a rare possibility of changes in blood pressure, heart rate, or rhythm with Combivent Respimat. Individuals with high blood pressure or heart conditions should be cautious, especially when exceeding the recommended dosage. Contact your doctor if you experience dizziness, fatigue, tremors, rapid heartbeat, or weakness.

• Eye Health Concerns: Combivent Respimat may increase eye pressure, potentially worsening or causing glaucoma. Inform your eye doctor if you have glaucoma or other eye issues, and report any vision changes. Avoid spraying the medication in your eyes as it can cause pain, discomfort, or blurry vision.

• Urinary Problems: Those with urinary or prostate issues should use Combivent Respimat carefully, as it may lead to difficulty urinating. Consult your healthcare provider if you encounter such symptoms.

• Severe Allergic Reactions: Combivent Respimat can trigger serious allergic reactions, including facial swelling, shock, or anaphylaxis. Obtain emergency medical help if you notice hives, rash, swelling of the face, lips, or tongue, or difficulty breathing.

• Low Potassium Levels: This medication can lower blood potassium levels, particularly if overused. Symptoms include tiredness, weakness, muscle cramps, and a racing heart. Do not exceed the prescribed dosage and seek medical advice if breathing issues persist.

Contraindications: Avoid using Combivent Respimat if you have allergies to atropine, ipratropium, albuterol, or similar medications (e.g., anticholinergics). Consult your healthcare provider if any of these conditions apply to you before using this medication.

When taking this medication, some common side effects may occur, such as headache, dizziness, and cough. You might also experience symptoms resembling a common cold or upper respiratory infection, as well as bronchitis, which are usually mild. If these persist or worsen, it's advisable to consult your healthcare provider for guidance.

Other effects might include nausea, dry mouth, shaking, nervousness, or constipation. Some users report flu-like symptoms, chest discomfort, or a racing heart. While these can be concerning, they are generally manageable. However, be mindful of any changes and seek advice if necessary.

It's important to monitor your blood pressure as this medication can cause an increase. In rare instances, there might be a sudden worsening of breathing problems immediately after use, requiring urgent medical attention. Serious side effects such as difficult or painful urination, muscle cramps, or eye problems like pain or vision changes should prompt immediate contact with a healthcare professional.

A severe allergic reaction, though rare, is a critical concern. Symptoms such as rash, swelling, severe dizziness, or trouble breathing necessitate immediate medical help. Always stay alert to any unexpected or severe symptoms and consult your healthcare provider to ensure safe use of the medication.

When taking Combivent Respimat, which contains Ipratropium and Albuterol, it is important to be aware of potential interactions with other medications. You should inform your doctor and pharmacist about all medications and supplements you are currently using, including prescription, over-the-counter, vitamins, and herbal products. While not all possible interactions are listed, there are certain drugs that may require caution:

• Similar Medications: Avoid using Levalbuterol alongside albuterol, as they are very similar.

• Typically Not Recommended: Using Combivent Respimat with medications such as Acebutolol, Amitriptyline, Atenolol, Bisoprolol, Carvedilol, and many others listed may not be recommended. However, in some situations, your doctor might prescribe them together and adjust the dosage or frequency.

• Increased Side Effects Risk: Combining Combivent Respimat with betel nut or Digoxin might heighten the risk of side effects, yet these combinations might be necessary for your treatment. Your doctor may alter dosing if both are required.

Always consult with your healthcare provider to determine the best course of action if these medications are part of your treatment plan.