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High Prolactin

High prolactin, or hyperprolactinemia, refers to elevated levels of prolactin hormone in the blood. It can be caused by pregnancy, medications, tumors, or underlying medical conditions. Symptoms vary between genders and may include irregular periods, milk discharge, infertility, and decreased libido. Treatment options depend on the cause and may involve medications or addressing the underlying condition. Seeking medical attention is crucial for diagnosis and appropriate management.

Best medications for High Prolactin

Drug NameClassRouteStandard DosagePrice
CabergolineErgot DerivativesOral0.5 MGfrom$30.77
ParlodelErgot DerivativesOral2.5, 5 MGfrom$64.71

What is High Prolactin?

High prolactin, also known as hyperprolactinemia, is a medical condition characterized by elevated levels of prolactin hormone in the blood. Prolactin is primarily responsible for stimulating milk production in women after childbirth. However, it also plays a role in other bodily functions.

Causes of High Prolactin

There are several possible causes of high prolactin levels:

  • Pregnancy and lactation: During pregnancy and breastfeeding, prolactin levels naturally rise to support milk production.

  • Prolactinoma: A prolactinoma is a noncancerous tumor of the pituitary gland that leads to excessive prolactin production.

  • Medications: Certain medications, such as antipsychotics, antidepressants, and medications used to treat acid reflux, can increase prolactin levels.

  • Hypothyroidism: Underactive thyroid gland can cause high prolactin levels.

  • Stress and exercise: Intense stress or physical exertion may temporarily raise prolactin levels.

  • Other causes: Certain underlying medical conditions, including chronic kidney disease, liver disease, and polycystic ovary syndrome (PCOS), can also be associated with elevated prolactin levels.

Symptoms of High Prolactin

In women, high prolactin levels can cause:

  • Irregular menstrual periods or complete absence of periods (amenorrhea)

  • Galactorrhea, which is the spontaneous flow of milk from the breasts outside of pregnancy or breastfeeding

  • Infertility or difficulty getting pregnant

  • Decreased libido

Men with high prolactin levels may experience:

  • Erectile dysfunction

  • Enlargement of breast tissue (gynecomastia)

  • Decreased libido

Treatment for High Prolactin

Treatment options for high prolactin depend on the underlying cause:

  • Prolactinoma: Prolactinomas are usually treated with medications called dopamine agonists, which reduce prolactin secretion and shrink the tumor.

  • Medication-related: If medications are causing elevated prolactin levels, alternative treatments may be considered, or the dosage may be adjusted.

  • Hypothyroidism: Treating the underlying hypothyroidism with thyroid hormone replacement therapy can help normalize prolactin levels.

  • Other causes: Treating the underlying medical conditions, such as kidney or liver disease, can often reduce prolactin levels.

Final Thoughts

If you are experiencing symptoms suggestive of high prolactin, it is important to seek medical attention. A healthcare provider can perform tests to measure your prolactin levels and identify the underlying cause. Diagnosing and treating the underlying condition can help normalize prolactin levels and alleviate associated symptoms.