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This medication comes with important safety warnings that should be carefully reviewed to ensure safe use. If you have any concerns or questions, please speak with your healthcare provider.

• Hormone Issues and Withdrawal: Excessive absorption of flurandrenolide (Cordran) through the skin can occur, especially when applied to large skin areas, used for extended periods, or when the treated area is covered with tight bandages. This can lead to changes in stress hormone levels, such as cortisol, potentially causing symptoms like fatigue, nausea, and muscle pain. These symptoms generally subside after discontinuation of the medication but may require further treatment in severe cases. In rare instances, elevated blood sugar levels and delayed growth in children may occur. Therefore, it is crucial to follow your prescriber's instructions precisely, particularly in children, when using flurandrenolide (Cordran).

• Skin Irritation: It is advised not to apply flurandrenolide (Cordran) to the face unless directed by your healthcare provider, as it can cause skin thinning and damage even with short-term use. Use the smallest effective amount for the shortest duration necessary, especially when applying the medication to skin folds or the face.

• New or Worsened Skin Infections: Flurandrenolide (Cordran) may reduce your body's ability to combat infections, including those on the skin. If you develop a new skin infection, it is important to use an appropriate antifungal or antibacterial treatment. Prolonged use of this medication increases the risk of infection. If you notice symptoms such as redness, swelling, pain, or pus at the application site, discontinue use and consult your healthcare provider immediately.

Contraindications:

This medication should not be used under certain conditions due to potential serious health risks. If any of the following apply to you, consult your healthcare provider:

• On skin folds or areas where skin rubs together (specifically for Cordran Tape).
• On wounds or lesions that are leaking fluid (specifically for Cordran Tape).

Always adhere to these guidelines to minimize risks and ensure the effective and safe use of the medication.

When using Cordran (Flurandrenolide), it's important to be aware of potential interactions with other medications and health conditions. Cordran is a topical corticosteroid applied to the skin to reduce inflammation and itching associated with various skin conditions.

Drug Interactions:

Cordran may interact with other medications, particularly other corticosteroids. Using multiple corticosteroids simultaneously, whether applied to the skin or taken orally, can increase the risk of side effects. Therefore, it's advisable to avoid concurrent use of Cordran with other corticosteroid medications unless directed by a healthcare provider.

Disease Interactions:

Certain health conditions may influence how your body responds to Cordran:

• Diabetes: Topical corticosteroids like Cordran can elevate blood sugar levels, which may be a concern for individuals with diabetes.

• Infections: Applying Cordran to infected skin areas can worsen the infection. It's important to ensure that the skin is free from infections before using this medication.

• Hyperadrenocorticism (Cushing's Syndrome): Prolonged use of corticosteroids can lead to this condition, characterized by symptoms such as weight gain, high blood pressure, and skin changes.

• Ocular Toxicities: Avoid applying Cordran near the eyes, as it can increase the risk of eye-related side effects.

• Diaper Rash: Using Cordran in the diaper area of infants can lead to increased absorption and potential side effects.

General Precautions:

To minimize the risk of interactions and side effects:

• Avoid Occlusive Dressings: Do not bandage, wrap, or cover the treated area unless instructed by your healthcare provider, as this can increase absorption of the medication.

• Limit Use on Sensitive Areas: Avoid using Cordran on the face, groin, or armpits unless specifically directed by a healthcare professional.

• Monitor for Side Effects: Be vigilant for signs of adverse reactions, such as skin thinning, stretch marks, or increased blood sugar levels, and report them to your healthcare provider promptly.

Always inform your healthcare provider about all medications, supplements, and health conditions before starting Cordran to ensure safe and effective use.