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This medication comes with several important safety warnings that you should review carefully. If you have any concerns, please discuss them with your healthcare provider.

• Hormonal Changes: Excessive absorption of topical steroids like clobetasol through the skin can disrupt the natural production of stress hormones, affecting various bodily functions. This may result in elevated blood sugar levels or increased skin bruising. Risks are higher with prolonged use, application over large skin areas, or when covering treated areas with a bandage. To minimize these risks, your healthcare provider will prescribe the lowest effective dose for the shortest duration. Avoid using clobetasol for more than two weeks at a time (or four weeks if using the shampoo), unless instructed otherwise by your provider. Periodic lab tests may be necessary to monitor hormone levels.

• Increased Blood Sugar Levels: Prolonged use of clobetasol or its application over extensive skin areas can result in elevated blood sugar levels, potentially leading to diabetes. If you have diabetes, you may need to monitor your blood sugar levels regularly while using this medication to ensure its safety.

• Skin Infections: Clobetasol may lower the body's ability to fight infections, including those affecting the skin. If you notice signs of infection such as redness, pain, swelling, or pus at the application site, discontinue use immediately and contact your healthcare provider. Prompt treatment with appropriate antifungal or antibacterial medications is crucial.

• Skin Reactions: Using clobetasol longer than recommended can increase the risk of adverse skin reactions such as thinning, stretch marks, spider veins, burning, itching, irritation, dry skin, inflamed hair follicles, changes in skin color, or rash. Some of these changes may be permanent. Your healthcare provider will prescribe the lowest possible dose to manage your symptoms for the shortest time necessary. Inform your provider immediately if you experience any new or worsening skin issues.

There are no specific contraindications provided for this medication. However, always follow your healthcare provider's guidance and report any unusual symptoms or concerns promptly.

When using this medication, you may initially experience mild side effects such as burning, stinging, itching, irritation, redness, dry skin, or acne, especially when applied to the scalp. These effects usually subside as your body adjusts. If they continue or worsen, seek advice from your healthcare provider. Some individuals may also notice skin discoloration, hair loss, or small red bumps on the skin.

There are more significant side effects that warrant immediate medical attention, including stretch marks, thinning of the skin, excessive hair growth, or worsening skin infections. In rare cases, the medication might be absorbed into the bloodstream, particularly in children or those using it extensively over large areas, leading to symptoms such as unusual tiredness, weight loss, swelling in the ankles or feet, increased thirst or urination, and vision problems.

Allergic reactions are very rare but serious. If you experience a rash, severe dizziness, swelling, or breathing difficulties, seek emergency help immediately. Always remain vigilant for any other unexpected side effects and consult your healthcare provider if they occur.