HomeDrug ClassesACE Inhibitor / Thiazide Diuretic Combinations

ACE Inhibitor / Thiazide Diuretic Combinations: Uses, Common Brands, and Safety Info

ACE inhibitor/thiazide diuretic combinations are commonly prescribed to treat hypertension. They lower blood pressure by relaxing blood vessels and increasing urine production. Common brands include Zestoretic, Prinzide, Accuretic, Capozide, and Vaseretic. These combinations are generally safe but may cause side effects like dizziness and low potassium levels. Regular monitoring and check-ups are important.


ACE inhibitors/thiazide diuretic combinations are a class of medications commonly prescribed to treat hypertension, also known as high blood pressure. These drugs work together to lower blood pressure by different mechanisms. ACE inhibitors help relax blood vessels, allowing blood to flow more easily, while thiazide diuretics increase urine production, reducing the amount of fluid in the blood vessels and reducing the workload on the heart.

Common Brands

There are several commonly prescribed ACE inhibitor/thiazide diuretic combinations available on the market. Some well-known brand names include: 1. Zestoretic (lisinopril/hydrochlorothiazide) 2. Prinzide (lisinopril/hydrochlorothiazide) 3. Accuretic (quinapril/hydrochlorothiazide) 4. Capozide (captopril/hydrochlorothiazide) 5. Vaseretic (enalapril/hydrochlorothiazide) These brand-name combinations contain different ACE inhibitors along with the thiazide diuretic hydrochlorothiazide. Your healthcare provider will determine the most appropriate combination for you based on your specific needs and medical history.


When taken as prescribed, ACE inhibitor/thiazide diuretic combinations are generally safe and well-tolerated. However, as with any medication, there are some safety considerations to keep in mind. It is important to inform your healthcare provider if you have any allergies, especially to similar medications or substances. Additionally, let your healthcare provider know about any other medications you are taking, as drug interactions can occur. Common side effects of ACE inhibitor/thiazide diuretic combinations may include dizziness, headache, cough, increased urination, and low potassium levels. If you experience any severe or persistent side effects, it is important to contact your healthcare provider immediately. These medications may not be suitable for individuals with specific medical conditions, such as kidney disease, liver disease, or diabetes. It is essential to discuss your medical history with your healthcare provider before starting on an ACE inhibitor/thiazide diuretic combination. Regular monitoring of blood pressure and kidney function may be required while taking these medications. It is crucial to attend regular check-ups with your healthcare provider to ensure that the medication is effectively managing your condition. In conclusion, ACE inhibitor/thiazide diuretic combinations are commonly used to treat high blood pressure. They are available under various brand names and work by relaxing blood vessels and promoting diuresis. While generally safe, it is important to follow your healthcare provider's instructions, report any side effects, and attend regular check-ups to monitor your blood pressure and overall health.

List of ACE Inhibitor / Thiazide Diuretic Combinations