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Hepatitis B NRTIs: Uses, Common Brands, and Safety Info

"Hepatitis B NRTIs are antiviral medications used to treat chronic Hepatitis B infection by inhibiting viral replication. They are effective at reducing the viral load and improving liver function. Common brands include Viread, Baraclude, and Zeffix. These drugs may cause mild side effects like nausea and fatigue, but regular monitoring is necessary to avoid more serious complications. Hepatitis B NRTIs cannot cure the infection completely and should be used under medical supervision."

Hepatitis B NRTIs

Hepatitis B Nucleoside Reverse Transcriptase Inhibitors (NRTIs) are a class of antiviral medications used for the treatment of chronic Hepatitis B infection. These drugs work by inhibiting the reverse transcriptase enzyme, which is vital for the replication of the Hepatitis B virus. By disrupting viral replication, Hepatitis B NRTIs help to reduce the viral load in the body, slow down disease progression, and improve liver function.


Hepatitis B NRTIs are primarily used for the treatment of chronic Hepatitis B infection, a serious viral infection that affects the liver. These medications are highly effective in suppressing the replication of the Hepatitis B virus and reducing inflammation in the liver. They are particularly beneficial for individuals with elevated liver enzymes, active viral replication, and signs of liver damage.

In addition to their antiviral properties, some Hepatitis B NRTIs also possess immunomodulatory effects. This means that they can help boost the body's immune response against the Hepatitis B virus, further aiding in the control of the infection.

Common Brands

There are several commonly prescribed Hepatitis B NRTIs available in the market. Some well-known brands include:

These brands may be available in different formulations, such as tablets or oral solutions, and may require different dosing regimens. It is essential to follow the specific instructions provided by your healthcare provider or pharmacist.


Hepatitis B NRTIs are generally safe and well-tolerated when used as prescribed. However, like any medication, they can cause side effects in some individuals. Common side effects may include nausea, diarrhea, fatigue, headache, and abdominal pain. These side effects are usually mild and temporary, disappearing as the body adjusts to the medication.

Occasionally, Hepatitis B NRTIs can cause more serious side effects, such as liver toxicity or lactic acidosis. Therefore, regular monitoring of liver function and adherence to prescribed dosages are essential to ensure the safe use of these medications.

It is important to note that Hepatitis B NRTIs cannot cure Hepatitis B infection entirely. These medications are typically used as long-term therapy to control the virus and maintain liver health. Your healthcare provider will determine the most appropriate treatment plan based on your specific condition and medical history.

Always consult with a healthcare professional or specialist before starting or discontinuing any medication for Hepatitis B.

Viread (tenofovir disoproxil fumarate)

Viread is an FDA-approved Hepatitis B NRTI that comes in the form of tablets. It is taken orally once daily, preferably with food. Viread has demonstrated potent antiviral activity and good tolerability in clinical studies, making it a commonly prescribed option for Hepatitis B treatment.

Baraclude (entecavir)

Baraclude is another widely used Hepatitis B NRTI. It is available in tablet form and is taken orally once daily, with or without food.

List of Hepatitis B NRTIs