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Entecavir is a medication used to manage hepatitis B, but it comes with important safety warnings and precautions. It's crucial to understand these to ensure safe and effective use:

• Serious Liver and Lactic Acid Issues: Entecavir can rarely lead to serious, possibly fatal liver problems and lactic acid build-up in the blood (lactic acidosis). Immediate medical attention is necessary if you experience persistent nausea or vomiting, loss of appetite, abdominal pain, yellowing of the skin or eyes, dark urine, unusual tiredness or weakness, deep or rapid breathing, unusual drowsiness, muscle pain, coldness in arms or legs, or a fast or irregular heartbeat. These effects are more common in women and those who are obese.

• Hepatitis B Worsening After Stopping Treatment: Do not discontinue entecavir without consulting your healthcare provider. Stopping treatment can result in a resurgence or worsening of hepatitis B. If discontinuation is advised, regular blood tests for liver function and hepatitis B virus monitoring are essential, especially in the first few months post-treatment.

• Co-infection with HIV: Entecavir is not recommended for individuals with both HIV and hepatitis B who are not receiving effective HIV treatment. Taking entecavir can lead to resistance to certain HIV medications. An HIV test is necessary before starting entecavir and should be repeated periodically. Discuss with your healthcare provider for an appropriate treatment plan if you have both infections.

• Emergency Situations: In the event of symptoms suggesting lactic acidosis or severe liver problems, stop taking entecavir immediately and seek emergency medical help.

• Risk Factors: Women, obese individuals, and those with a history of liver problems are at higher risk for these side effects.

By adhering to these precautions and consulting your healthcare provider, you can manage hepatitis B effectively while minimizing potential risks.

When taking this medication, some common side effects you might experience include headaches, fatigue, dizziness, nausea, and higher liver lab results. These effects are generally mild, but if they persist or worsen, it’s advisable to consult your healthcare provider for guidance.

There are other side effects that have been reported, such as indigestion, diarrhea, and trouble sleeping. While these may be bothersome, they are typically not serious. However, if these symptoms become severe, reaching out to your healthcare provider is recommended.

It's important to be aware of rare but serious side effects that require immediate medical attention. These include symptoms of lactic acidosis, such as extreme tiredness, sudden weakness, fast and shallow breathing, loss of appetite, nausea, and vomiting. Additionally, signs of liver problems, like stomach pain and persistent tiredness, also warrant urgent medical care.

A very serious allergic reaction to this drug is rare, but if you experience symptoms such as rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing, seek medical assistance immediately. Always be attentive to how your body responds to the medication and consult your healthcare provider if you observe any concerning effects.