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Nausea, stomach upset, diarrhea, drowsiness, flushing, and numbness/tingling may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes, unusual weakness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Some products that may interact with this drug are: altretamine, cisplatin, levodopa (when used without carbidopa), folic acid antagonists (such as methotrexate), hydantoins (such as phenytoin, diphenylhydantoin), pyrimethamine. This product may interfere with certain lab tests (such as intrinsic factor antibodies, certain urobilinogen tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this product.