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This medication carries important safety warnings and potential risks that need to be carefully considered. Please review the following information and consult your healthcare provider if you have any concerns:

• Kidney Problems: This medication can lead to severe, potentially fatal kidney issues. The risk is heightened for individuals over 65, those with pre-existing kidney problems, diabetes, blood infections (sepsis), dehydration, or high blood protein levels (paraproteinemia). It is also increased if you are taking other kidney-harming drugs, such as gentamicin.

• Blood Clot Risk: There is an increased risk of blood clots, which can lead to serious conditions such as heart attack, stroke, or pulmonary embolism. Factors that elevate this risk include advanced age, immobility, a history of blood clots or heart conditions, the use of estrogen-containing products, and the presence of central IV lines.

• Allergic Reactions: Serious allergic reactions, including anaphylaxis, are possible. Symptoms may include dizziness, nausea, difficulty breathing, and swelling around the eyes, lips, or tongue. If these symptoms occur, seek immediate medical attention.

• Brain Inflammation: Rare cases of brain inflammation (aseptic meningitis) have been reported. Symptoms, such as severe headache, neck stiffness, and fever, may appear within hours to days post-infusion and typically resolve after stopping treatment. Contact your doctor if these symptoms arise.

• Anemia: The medication may cause rapid destruction of red blood cells, leading to anemia. Your healthcare provider may monitor your blood cell counts during treatment. Report symptoms like tiredness, dizziness, and weakness to your provider.

• Lung Issues: Infusion may result in transfusion-related acute lung injury (TRALI), characterized by severe breathing problems and chest pain. It usually occurs within 1 to 6 hours after infusion. Alert your healthcare provider immediately if you experience these symptoms.

• Infection Risk: Since the medication is derived from human blood products, there is a slight risk of viral or bacterial infection, despite stringent safety measures. Notify your healthcare provider if you experience unusual symptoms like confusion or balance issues.

• Contraindications: Do not use this medication if you have a severe allergy to immunoglobulin G, immunoglobulin A deficiency with antibodies against IgA, or a history of allergic reaction to immune globulin products.

Emergency measures: In case of an overdose or severe reaction, seek emergency medical attention immediately. Always discuss the risks and benefits of this medication with your healthcare provider, especially if you have any underlying conditions or are on concurrent medications that may interact.

When taking this medication, you might experience some mild side effects, which are generally temporary and manageable. Commonly reported effects include headaches, fatigue, fever, nausea, diarrhea, vomiting, cough, chills, dizziness, and pain in the arms or legs. If these symptoms persist or worsen, it is advisable to consult your healthcare provider for guidance.

While many people do not experience severe side effects, certain rare conditions warrant prompt medical attention. Aseptic meningitis syndrome, a serious brain inflammation, can develop within hours to a couple of days after treatment, characterized by severe headaches, stiff neck, drowsiness, fever, sensitivity to light, eye pain, or nausea/vomiting. Seek immediate help if you notice these symptoms. Rarely, lung issues might occur within 1 to 6 hours post-treatment, manifesting as difficulty breathing, chest pain, blue lips or skin, and fever. These symptoms necessitate urgent care.

An allergic reaction to this medication is highly uncommon but can be severe. Look out for symptoms like rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing, and seek medical help immediately if they occur. This summary does not cover all possible side effects. If you notice any other unusual effects, reach out to your healthcare provider for advice.