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This medication is associated with several significant safety concerns that patients and healthcare professionals should be aware of. Below are the key risks, precautionary measures, and emergency actions to consider:

• Blood Clots: This medication may increase the risk of developing blood clots, which can lead to serious conditions such as heart attack, stroke, or pulmonary embolism. Factors that heighten this risk include older age, dehydration, prolonged immobility, presence of a central venous catheter, history of blood clots, heart disease, or the use of estrogen-containing products. To mitigate this risk, healthcare providers may opt to administer the medication more slowly or in a less concentrated form and ensure the patient is well-hydrated. Seek immediate medical attention if you experience symptoms such as difficulty breathing, chest pain, sudden dizziness, swelling or warmth in the legs, severe headache, or sudden weakness.

• Allergic Reactions: Severe allergic reactions, including anaphylaxis, may occur. Symptoms such as dizziness, difficulty breathing, swelling of the face or throat, and nausea require urgent medical care.

• Brain Inflammation: Although rare, some individuals may experience aseptic meningitis, characterized by severe headache, neck stiffness, and fever. These symptoms typically resolve after discontinuing the medication. Contact your healthcare provider if you experience any of these symptoms.

• Kidney Problems: This medication can cause severe kidney issues, especially in patients with pre-existing conditions such as diabetes or those taking nephrotoxic drugs. Regular monitoring of kidney function is recommended, and treatment may be discontinued if kidney health deteriorates. Symptoms to watch for include changes in urination, fatigue, dry skin, and muscle cramps.

• Red Blood Cell Breakdown: The medication can lead to the rapid destruction of red blood cells. It is important for healthcare providers to monitor blood counts during treatment. Symptoms such as fatigue, dizziness, and weakness should be reported to your healthcare provider.

• Lung Issues: There is a risk of transfusion-related acute lung injury (TRALI) characterized by severe respiratory distress, chest pain, and fever. Immediate medical attention is required if these symptoms appear.

• Infection Risk: Since this medication is derived from human blood products, there is a potential, albeit low, risk of viral infection. Inform your provider if you experience symptoms of infection, such as confusion or balance problems.

Contraindications:

• Do not use this medication if you have a severe allergy to human immune globulin, hyperprolinemia type I or II, or an IgA deficiency with antibodies against IgA and a history of allergic reactions.

Consult your healthcare provider for further guidance and to ensure safe usage of this medication given your medical history and current health status.

When using this medication, some individuals may experience mild side effects, which are generally not a cause for concern. Common reactions include mild swelling, redness, or itching at the injection site, which typically diminishes as your body adapts. Other mild effects may include headache, upset stomach, fever, nausea, diarrhea, sore throat, cough, or pain. It is important to inform your healthcare provider if any of these symptoms persist or worsen.

Less frequently, individuals might also encounter fatigue, back pain, rash, or pain in the arms or legs. If you experience any of these, especially if they are bothersome, consulting your healthcare provider is advisable.

Although rare, some side effects can be serious and warrant immediate medical attention. These include signs of kidney problems such as changes in urine output, sudden weight gain, or a fast heartbeat. Very serious side effects requiring urgent care include severe headache, stiff neck, eye pain, light sensitivity, or difficulty breathing.

In exceptional cases, a serious allergic reaction may occur, characterized by a rash, significant swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. If these symptoms arise, seek medical help immediately. Always report any other effects not listed here to your healthcare provider.