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This medication carries significant safety concerns that need careful consideration before use. Below are important risks and precautions associated with its use. Always consult with your healthcare provider to discuss any of these conditions or risks.

• Kidney Issues: This medication can lead to severe and potentially life-threatening kidney problems. The risk is heightened in older adults, those with existing kidney issues, diabetes, sepsis, or dehydration, and those using other kidney-harming drugs like gentamicin. It is vital to stay adequately hydrated and have your kidney function monitored by your doctor. Symptoms of kidney failure include fatigue, difficulty sleeping, dry and itchy skin, reduced appetite, and muscle cramps. If these occur, contact your healthcare provider immediately.

• Blood Clots: The medication can increase the risk of blood clots, especially in individuals with a history of clots, heart disease, immobility, or those using estrogen-containing products. Symptoms can vary based on the clot's location but may include chest pain, difficulty breathing, swelling or warmth in the legs, or weakness in the face, arms, or legs. Seek emergency medical attention if you experience any of these symptoms.

• High Protein and Low Sodium Levels: The medication may lead to elevated protein levels in your blood and low sodium levels. Regular lab tests will be conducted to monitor these potential side effects, and your dosage may be adjusted accordingly.

• Serious Allergic Reactions: There is a risk of severe allergic reactions, including anaphylaxis. Immediate medical care is necessary if you experience dizziness, a choking sensation, swelling around the eyes, lips, or tongue, or difficulty breathing.

• Brain Swelling (Aseptic Meningitis): Rarely, this medication can cause brain swelling. Symptoms like severe headache, neck stiffness, sleepiness, fever, sensitivity to light, or nausea may appear within hours to two days after administration. Contact your doctor if you experience these symptoms.

• Hemolytic Anemia: This condition results from the breakdown of red blood cells and may present as tiredness, dizziness, and weakness. Blood cell counts will be monitored throughout your treatment.

• Lung Problems (TRALI): This medication can cause transfusion-related acute lung injury, characterized by severe breathing issues, fluid in the lungs, and low blood oxygen levels. These symptoms typically manifest 1 to 6 hours post-infusion. Notify your doctor if you experience any respiratory difficulties.

• Infection Risk: As this medication is derived from human blood products, there is a minimal risk of viral infection. However, due to rigorous screening and manufacturing protocols, this risk is low. Inform your healthcare provider immediately if you feel unwell or experience confusion, anxiety, or balance issues.

Contraindications:

• Do not use this medication if you have a severe allergy to human immune globulin or if you have low immunoglobulin A levels with IgA antibodies. Consult your healthcare provider if these conditions apply to you.

Always discuss potential risks and benefits with your healthcare provider before beginning treatment.

When taking this medication, some common side effects may occur. These include reactions at the injection site, cough, headache, nausea, fever, joint pain, and mild sinus inflammation. These effects are usually mild, but if they persist or worsen, it’s important to consult your healthcare provider for advice and reassurance.

In addition to the common side effects, some patients may experience other symptoms such as tiredness, upper respiratory infections, sore throat, depression, vomiting, high blood pressure, chills, or bruising. If these symptoms occur, especially if they are severe, contacting your healthcare provider is recommended to ensure appropriate care.

There are also rare but serious side effects that require immediate medical attention. These include kidney problems, blood clots, serious allergic reactions, and swelling or inflammation of the brain. Symptoms of these conditions can range from tiredness and trouble sleeping to difficulty breathing, severe headaches, and confusion. Hemolytic anemia and lung problems are also potential severe side effects, with symptoms like dizziness, weakness, yellowing of the skin, or difficulty breathing. If any of these serious side effects occur, it is crucial to seek urgent medical care promptly.