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The use of somatropin injections, such as Omnitrope, carries certain risks and requires careful consideration. It is essential to be aware of the potential dangers and precautions associated with this medication. Below, we outline important safety information and warnings to help guide your use of somatropin. Always consult your healthcare provider if you have any concerns.

• Increased Risk of Mortality in Critical Illness: Avoid using somatropin if you have a critical illness resulting from open-heart or abdominal surgery, severe injuries, or respiratory problems, as it can elevate the risk of death.

• Sudden Death in Children with Prader-Willi Syndrome: Children with Prader-Willi syndrome who are obese, have airway blockages, or undiagnosed respiratory infections should not use somatropin, as there is a risk of sudden death. Children without these risk factors may use the medication but require close monitoring for respiratory symptoms.

• Severe Allergic Reactions: Omnitrope can cause serious allergic reactions, including anaphylaxis. Seek immediate medical help if you experience dizziness, choking, difficulty breathing, nausea, or swelling around the eyes, lips, or tongue.

• Cancer Concerns: Do not use somatropin if you or your child has active cancer. The medication may increase the risk of new cancers, so inform your provider of any cancer history.

• High Blood Sugar and Diabetes Risk: Somatropin can cause elevated blood sugar levels, increasing the risk of diabetes, particularly in individuals who are obese, have Turner syndrome, or have a family history of diabetes. Regular blood sugar monitoring is advised.

• Intracranial Hypertension: Some users may develop high blood pressure in the brain, leading to symptoms like vision changes, headaches, nausea, and vomiting. These symptoms usually resolve after stopping or reducing the dose of the medication.

• Fluid Retention and Swelling: Omnitrope may cause fluid retention, resulting in swelling of the arms and legs, muscle pain, or carpal tunnel syndrome. Consult your provider if these symptoms occur.

• Low Cortisol Levels: The medication can lower cortisol levels, especially in individuals taking certain steroid hormones. Monitor for signs of low cortisol.

• Bone Issues in Children: Rapidly growing children may experience a condition where the thigh bone slips out of position. Report any knee or hip pain or limping to your provider.

• Pancreatitis: Though rare, somatropin may cause pancreatitis, characterized by abdominal pain radiating to the back, nausea, and vomiting. Discontinue use and seek medical attention if these symptoms arise.

Contraindications indicate when somatropin should not be used due to potential health risks:

• Short-term critical illness from surgery, severe injuries, or respiratory issues.
• Active cancer.
• Severe diabetic eye damage (diabetic retinopathy).
• Severely obese children with Prader-Willi syndrome, serious breathing issues, or sleep apnea.
• Children who have stopped growing or have closed growth plates (epiphyses).

Always consult your healthcare provider before starting or discontinuing this medication, especially if any of these conditions apply to you or your child.

When taking this medication, some common side effects may include headaches, nausea, vomiting, tiredness, muscle pain, bruising, and leg pain. These are generally mild and often do not require medical attention unless they persist or worsen. Swelling in the arms and legs, joint pain, and upper respiratory infections are also reported and can vary in frequency. While these can be bothersome, they are typically manageable.

However, there are more serious side effects that necessitate prompt medical attention. Watch for persistent nausea or vomiting, unusual tiredness, rapid or slow heartbeat, ear pain or itching, and any change in mole appearance. Additionally, a significant increase in thirst or urination, severe stomach pain, or swelling of the hands, ankles, or feet should be reported immediately.

For children with Prader-Willi syndrome, this medication may pose a risk of severe lung or breathing problems, especially if they are male, severely overweight, or have existing respiratory issues. Symptoms like heavy snoring or sleep apnea need to be monitored closely. Somatropin might also elevate the risk of tumors or cancer, so a discussion regarding its risks and benefits is important.

Lastly, though rare, a very serious allergic reaction may occur, marked by symptoms such as rash, severe swelling of the face, tongue, or throat, dizziness, or trouble breathing. Immediate medical help is necessary if these occur. Always consult your healthcare provider if you notice any other side effects not listed here.