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You may experience dizziness, drowsiness, nausea, or vomiting when taking this medication. These side effects are generally mild and often resolve on their own. However, if they persist or worsen, it is important to consult with a healthcare professional for advice. Most people taking this medication do not experience serious side effects, which can be reassuring.

In rare cases, some individuals might experience a severe allergic reaction. This is a serious condition that requires immediate medical attention. Symptoms of a severe allergic reaction include rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, and difficulty breathing. If you observe any of these symptoms, seek medical help right away.

While this guide covers common side effects, it may not include all possible reactions. If you notice any other unexpected effects, please contact a healthcare provider for further guidance. Your safety and well-being are the top priority, so don't hesitate to reach out if you have any concerns.

Avoid combining this medication with certain MAO inhibitors, as it can lead to a severe and potentially life-threatening interaction. Do not use isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while on this treatment. Additionally, most MAO inhibitors should be avoided for at least two weeks before starting this medication. Consult your doctor for guidance on when to begin or discontinue use. Rolapitant is another product that may interact with this medication.

Both prescription and over-the-counter forms of Guaifenesin and dextromethorphan exist. To avoid taking more than one product containing these ingredients, carefully check the labels of all your medications.

Note that guaifenesin might interfere with certain laboratory tests, such as those measuring urine levels of specific acids, which can lead to inaccurate results. Ensure that all healthcare providers and laboratory staff are aware of your guaifenesin use.