Guanfacine

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Guanfacine is a medication prescribed to manage high blood pressure, particularly in individuals aged 12 and older. It functions by targeting receptors in the brain that reduce the action of norepinephrine, a chemical that normally increases blood pressure by tightening blood vessels. By decreasing this chemical's effect, guanfacine allows blood vessels to relax, enhancing blood flow and lowering heart rate, which in turn reduces blood pressure. Typically taken once daily, preferably at night, guanfacine may cause side effects such as sleepiness, dizziness, and dry mouth. It is important to consult with a healthcare professional before combining it with other medications, as interactions can exacerbate these side effects.
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1MG, Guanfacine (30 Tablets)

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CVS

$20.70

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Walgreens

$5.92

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Rite Aid

$8.57

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$12.87

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$17.45

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CVS

$20.70

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Guanfacine dosage forms

The average cost for 30 Tablets of Guanfacine at 1MG is $5.92 with a free coupon. This is 15.42% off the average retail price of $38.4
DosageQuantityPrice fromPer unit
1MG30 Tablets$5.92$0.2
2MG30 Tablets$10.19$0.34

Guanfacine Warnings

This medication comes with important safety warnings to ensure proper use and avoid potential risks. Carefully review the following information and consult your healthcare provider if you have any questions or concerns.

  • Extreme Sleepiness and Dizziness: Guanfacine may induce significant sleepiness and dizziness, particularly at higher doses. This can impair your cognitive functions, reaction time, and concentration. The risk increases if you are concurrently using other medications that cause drowsiness, such as benzodiazepines, anxiety medications, muscle relaxants, and sleep aids. Assess how guanfacine affects you before engaging in activities that require focus, such as driving. If you experience excessive drowsiness, contact your healthcare provider immediately. Increased risk factors include high doses of guanfacine, age 65 or older, alcohol consumption, and the use of other sedative medications.

  • Nervousness and Anxiety from Sudden Discontinuation: Abruptly stopping guanfacine can result in nervousness and anxiety, and in rare cases, elevated blood pressure. It is crucial not to discontinue the medication without consulting your healthcare provider. They can guide you through a gradual dose reduction to mitigate these effects safely.

No specific contraindications are noted for guanfacine at this time.

Guanfacine Side Effects

Common side effects:

  • dry mouth
  • sleepiness
  • dizziness
  • constipation
  • headache
  • weakness
  • tiredness

Less common but important to monitor:

  • confusion
  • leg cramps
  • upset stomach
  • erectile dysfunction

Serious side effects:

  • severe allergic reactions
  • rash
  • itching
  • swelling, especially of the face, tongue, or throat
  • severe dizziness
  • trouble breathing
  • mental or mood changes
  • depression
  • hallucinations
  • thoughts of suicide
  • irregular heartbeats
  • fainting
  • severely low blood pressure
  • feeling faint
  • lightheadedness
  • extreme tiredness

Guanfacine Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • Abametapir
  • Conivaptan
  • Fosnetupitant
  • Iobenguane I 131
  • Netupitant

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Guanfacine FAQs
What is the main use of guanfacine?

Guanfacine is primarily used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents. It is also used to manage high blood pressure, although this is less common.

Guanfacine is not classified as a mood stabilizer. It is primarily used to treat attention deficit hyperactivity disorder (ADHD) and is also used to manage high blood pressure.

Guanfacine can have several potential downsides or side effects. Common side effects include drowsiness, fatigue, dry mouth, and dizziness. Some individuals may also experience headaches, abdominal pain, or constipation. In certain cases, guanfacine can cause low blood pressure or a slow heart rate. It's important for individuals to discuss any concerns or side effects with their healthcare provider, as they can provide guidance on managing these effects or adjusting the medication if necessary.

Guanfacine is not typically used as a primary treatment for bipolar disorder. It is primarily prescribed for attention deficit hyperactivity disorder (ADHD) and sometimes for hypertension. While it may have some off-label uses, it is not commonly used to manage the mood swings associated with bipolar disorder. A healthcare provider should be consulted for appropriate treatment options for bipolar disorder.

Guanfacine is primarily used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents, as well as hypertension in adults. However, it may not be suitable for all adults due to potential side effects or interactions with other medications. Some adults may experience side effects such as drowsiness, dizziness, or low blood pressure, which can be problematic. Additionally, individuals with certain medical conditions or those taking specific medications may be advised against using guanfacine. It is important for adults to consult with a healthcare provider to determine if guanfacine is appropriate for their specific situation.